Abstract
Urinary zinc excretion is known to be elevated in subjects with sickle cell anemia. Sodium intake has been suggested to influence zinc excretion in normal subjects. In order to assess the effect of sodium on zinc excretion in subjects with sickle cell anemia, urinary zinc excretion was measured in thirteen children and adolescents with sickle cell anemia on both a high (140 mEq/day) and low (20 mEq/day) sodium intake. Urinary zinc excretion was elevated on both diets. The mean urinary zinc excretion on the high sodium diet (775 +/- 238 micrograms/24 h) was significantly lower (P less than .005) than that on the low sodium diet (947 +/- 344 micrograms/24 h). The zinc excretion did not correlate with calcium or magnesium excretion or aldosterone secretion rates or plasma renin activity. Although elevated, the urinary zinc excretion in patients with sickle cell anemia is still significantly lowered by increasing sodium intake.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 331-336 |
| Number of pages | 6 |
| Journal | Journal of the American College of Nutrition |
| Volume | 1 |
| Issue number | 4 |
| State | Published - 1982 |
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ASJC Scopus subject areas
- Food Science
- Medicine (miscellaneous)
Cite this
The effect of sodium intake on zinc excretion in patients with sickle cell anemia. / Matustik, M. C.; Chausmer, A. B.; Meyer, Walter.
In: Journal of the American College of Nutrition, Vol. 1, No. 4, 1982, p. 331-336.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The effect of sodium intake on zinc excretion in patients with sickle cell anemia.
AU - Matustik, M. C.
AU - Chausmer, A. B.
AU - Meyer, Walter
PY - 1982
Y1 - 1982
N2 - Urinary zinc excretion is known to be elevated in subjects with sickle cell anemia. Sodium intake has been suggested to influence zinc excretion in normal subjects. In order to assess the effect of sodium on zinc excretion in subjects with sickle cell anemia, urinary zinc excretion was measured in thirteen children and adolescents with sickle cell anemia on both a high (140 mEq/day) and low (20 mEq/day) sodium intake. Urinary zinc excretion was elevated on both diets. The mean urinary zinc excretion on the high sodium diet (775 +/- 238 micrograms/24 h) was significantly lower (P less than .005) than that on the low sodium diet (947 +/- 344 micrograms/24 h). The zinc excretion did not correlate with calcium or magnesium excretion or aldosterone secretion rates or plasma renin activity. Although elevated, the urinary zinc excretion in patients with sickle cell anemia is still significantly lowered by increasing sodium intake.
AB - Urinary zinc excretion is known to be elevated in subjects with sickle cell anemia. Sodium intake has been suggested to influence zinc excretion in normal subjects. In order to assess the effect of sodium on zinc excretion in subjects with sickle cell anemia, urinary zinc excretion was measured in thirteen children and adolescents with sickle cell anemia on both a high (140 mEq/day) and low (20 mEq/day) sodium intake. Urinary zinc excretion was elevated on both diets. The mean urinary zinc excretion on the high sodium diet (775 +/- 238 micrograms/24 h) was significantly lower (P less than .005) than that on the low sodium diet (947 +/- 344 micrograms/24 h). The zinc excretion did not correlate with calcium or magnesium excretion or aldosterone secretion rates or plasma renin activity. Although elevated, the urinary zinc excretion in patients with sickle cell anemia is still significantly lowered by increasing sodium intake.
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UR - http://www.scopus.com/inward/citedby.url?scp=0020437132&partnerID=8YFLogxK
M3 - Article
VL - 1
SP - 331
EP - 336
JO - Journal of the American College of Nutrition
JF - Journal of the American College of Nutrition
SN - 0731-5724
IS - 4
ER -