The effect of temazepam on respiration in elderly insomniacs with mild sleep apnea

Maria Hughes, C. M. Morin

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

This study evaluated the respiratory effect of temazepam in elderly subjects (mean age 65 ± 3.8 years), with mild sleep apnea. The 15 subjects of this report were enrolled in a larger randomized trial comparing pharmacological and behavioral treatments for insomnia. Seven subjects received temazepam 15-30 mg/day either alone or in combination with behavior therapy, and eight subjects received placebo or behavior therapy. The mean baseline respiratory disturbance index (RDI) was 9.2 ± 2.8 for the nondrug and 8.8 ± 5.3 for the temazepam group. There were no significant time, group or interaction effects. There was no increase in the RDI in elderly subjects with mild respiratory apnea receiving 15-30 mg of temazepam.

Original languageEnglish (US)
Pages (from-to)644-645
Number of pages2
JournalSleep
Volume18
Issue number8
StatePublished - 1995
Externally publishedYes

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Temazepam
Sleep Apnea Syndromes
Respiration
Behavior Therapy
Sleep Initiation and Maintenance Disorders
Apnea
Placebos
Pharmacology
Therapeutics

Keywords

  • Elderly
  • Insomniac
  • Respiration
  • Sleep apnea
  • Temazepam

ASJC Scopus subject areas

  • Physiology

Cite this

The effect of temazepam on respiration in elderly insomniacs with mild sleep apnea. / Hughes, Maria; Morin, C. M.

In: Sleep, Vol. 18, No. 8, 1995, p. 644-645.

Research output: Contribution to journalArticle

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