The Effect of Undiagnosed Diabetes on the Association between Self-Reported Diabetes and Cognitive Impairment among Older Mexican Adults

Brian Downer, Amit Kumar, Hemalkumar Mehta, Soham Al Snih, Rebeca Wong

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Purpose: To study the effect of undiagnosed diabetes on the relationship between self-reported diabetes and cognitive impairment. Methods: Data were from 1033 participants aged ≥60 from Wave III (2012) of the Mexican Health and Aging Study. Participants were classified as nondiabetic (n = 589), undiagnosed diabetic (n = 201), and self-reported diabetic (n = 243). Multivariate logistic regression models were used to estimate the relationship between self-reported diabetes and severity of cognitive impairment (nonimpaired, moderate impaired, severe impaired). Results: Self-reported diabetes was associated with significantly higher odds for severe, but not moderate, cognitive impairment (odds ratio [OR] = 2.70, 95% confidence interval [CI] = 1.39-5.32). The association between self-reported diabetes and severe cognitive impairment decreased by 6.3% when undiagnosed diabetics were included in the nondiabetic category and by 30.4% when undiagnosed diabetics were included in the self-reported diabetes category. Discussion: The association between self-reported diabetes and severe cognitive impairment is underestimated when undiagnosed diabetics are not differentiated from self-reported diabetics and nondiabetics.

Original languageEnglish (US)
Pages (from-to)564-569
Number of pages6
JournalAmerican Journal of Alzheimer's Disease and other Dementias
Volume31
Issue number7
DOIs
StatePublished - Nov 1 2016

Keywords

  • Mexico
  • cognition
  • dementia
  • diabetes
  • older adults

ASJC Scopus subject areas

  • General Neuroscience
  • Clinical Psychology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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