The effects of exercise training on elderly persons with cognitive impairment and dementia

A meta-analysis

Patricia Heyn, Beatriz C. Abreu, Kenneth Ottenbacher

Research output: Contribution to journalArticle

744 Citations (Scopus)

Abstract

Heyn P, Abreu BC, Ottenbacher KJ. The effects of exercise training on elderly persons with cognitive impairment and dementia: a meta-analysis. Arch Phys Med Rehabil 2004;85:1694-704. Objective To determine by meta-analysis whether physical exercises are beneficial for people with dementia and related cognitive impairments. Data sources Published articles and nonpublished manuscripts from 1970 to 2003 were identified by using electronic and manual searches. Key search words included exercise, rehabilitation, activities of daily living, dementia, Alzheimer's disease, aged, and geriatrics. Study selection Reviewed studies were limited to randomized trials evaluating exercise in persons 65 years of age or older with cognitive impairment. Studies included quantitative results (means, standard deviations, t tests, F tests) for physical fitness, physical functioning, cognition, or behavior outcomes. Data extraction One reviewer extracted data on study characteristics and findings. Selected articles were evaluated for methodologic quality by 2 raters. Data synthesis A total of 2020 subjects participated in the 30 trials that met the inclusion criteria. Summary effects were computed using a fixed effects (Hedge's gi) model. Significant summary effect sizes (ES) were found for strength (ES=.75; 95% confidence interval [CI], .58-.92), physical fitness (ES=.69; 95% CI, .58-.80), functional performance (ES=.59; 95% CI, .43-.76), cognitive performance (ES=.57; 95% CI, 0.43-1.17), and behavior (ES=.54; 95% CI, .36-.72). The overall mean ES between exercise and nonexercise groups for all outcomes was .62 (95% CI, .55-.70). Conclusions Exercise training increases fitness, physical function, cognitive function, and positive behavior in people with dementia and related cognitive impairments.

Original languageEnglish (US)
Pages (from-to)1694-1704
Number of pages11
JournalArchives of Physical Medicine and Rehabilitation
Volume85
Issue number10
DOIs
StatePublished - Oct 2004

Fingerprint

Dementia
Meta-Analysis
Confidence Intervals
Exercise
Physical Fitness
Cognition
Exercise Therapy
Manuscripts
Information Storage and Retrieval
Activities of Daily Living
Geriatrics
Cognitive Dysfunction
Alzheimer Disease

Keywords

  • Alzheimer disease
  • Dementia
  • Exercise
  • Meta-Analysis
  • Rehabilitation

ASJC Scopus subject areas

  • Rehabilitation

Cite this

The effects of exercise training on elderly persons with cognitive impairment and dementia : A meta-analysis. / Heyn, Patricia; Abreu, Beatriz C.; Ottenbacher, Kenneth.

In: Archives of Physical Medicine and Rehabilitation, Vol. 85, No. 10, 10.2004, p. 1694-1704.

Research output: Contribution to journalArticle

@article{8561285518a949ad8465f98baa55de25,
title = "The effects of exercise training on elderly persons with cognitive impairment and dementia: A meta-analysis",
abstract = "Heyn P, Abreu BC, Ottenbacher KJ. The effects of exercise training on elderly persons with cognitive impairment and dementia: a meta-analysis. Arch Phys Med Rehabil 2004;85:1694-704. Objective To determine by meta-analysis whether physical exercises are beneficial for people with dementia and related cognitive impairments. Data sources Published articles and nonpublished manuscripts from 1970 to 2003 were identified by using electronic and manual searches. Key search words included exercise, rehabilitation, activities of daily living, dementia, Alzheimer's disease, aged, and geriatrics. Study selection Reviewed studies were limited to randomized trials evaluating exercise in persons 65 years of age or older with cognitive impairment. Studies included quantitative results (means, standard deviations, t tests, F tests) for physical fitness, physical functioning, cognition, or behavior outcomes. Data extraction One reviewer extracted data on study characteristics and findings. Selected articles were evaluated for methodologic quality by 2 raters. Data synthesis A total of 2020 subjects participated in the 30 trials that met the inclusion criteria. Summary effects were computed using a fixed effects (Hedge's gi) model. Significant summary effect sizes (ES) were found for strength (ES=.75; 95{\%} confidence interval [CI], .58-.92), physical fitness (ES=.69; 95{\%} CI, .58-.80), functional performance (ES=.59; 95{\%} CI, .43-.76), cognitive performance (ES=.57; 95{\%} CI, 0.43-1.17), and behavior (ES=.54; 95{\%} CI, .36-.72). The overall mean ES between exercise and nonexercise groups for all outcomes was .62 (95{\%} CI, .55-.70). Conclusions Exercise training increases fitness, physical function, cognitive function, and positive behavior in people with dementia and related cognitive impairments.",
keywords = "Alzheimer disease, Dementia, Exercise, Meta-Analysis, Rehabilitation",
author = "Patricia Heyn and Abreu, {Beatriz C.} and Kenneth Ottenbacher",
year = "2004",
month = "10",
doi = "10.1016/j.apmr.2004.03.019",
language = "English (US)",
volume = "85",
pages = "1694--1704",
journal = "Archives of Physical Medicine and Rehabilitation",
issn = "0003-9993",
publisher = "W.B. Saunders Ltd",
number = "10",

}

TY - JOUR

T1 - The effects of exercise training on elderly persons with cognitive impairment and dementia

T2 - A meta-analysis

AU - Heyn, Patricia

AU - Abreu, Beatriz C.

AU - Ottenbacher, Kenneth

PY - 2004/10

Y1 - 2004/10

N2 - Heyn P, Abreu BC, Ottenbacher KJ. The effects of exercise training on elderly persons with cognitive impairment and dementia: a meta-analysis. Arch Phys Med Rehabil 2004;85:1694-704. Objective To determine by meta-analysis whether physical exercises are beneficial for people with dementia and related cognitive impairments. Data sources Published articles and nonpublished manuscripts from 1970 to 2003 were identified by using electronic and manual searches. Key search words included exercise, rehabilitation, activities of daily living, dementia, Alzheimer's disease, aged, and geriatrics. Study selection Reviewed studies were limited to randomized trials evaluating exercise in persons 65 years of age or older with cognitive impairment. Studies included quantitative results (means, standard deviations, t tests, F tests) for physical fitness, physical functioning, cognition, or behavior outcomes. Data extraction One reviewer extracted data on study characteristics and findings. Selected articles were evaluated for methodologic quality by 2 raters. Data synthesis A total of 2020 subjects participated in the 30 trials that met the inclusion criteria. Summary effects were computed using a fixed effects (Hedge's gi) model. Significant summary effect sizes (ES) were found for strength (ES=.75; 95% confidence interval [CI], .58-.92), physical fitness (ES=.69; 95% CI, .58-.80), functional performance (ES=.59; 95% CI, .43-.76), cognitive performance (ES=.57; 95% CI, 0.43-1.17), and behavior (ES=.54; 95% CI, .36-.72). The overall mean ES between exercise and nonexercise groups for all outcomes was .62 (95% CI, .55-.70). Conclusions Exercise training increases fitness, physical function, cognitive function, and positive behavior in people with dementia and related cognitive impairments.

AB - Heyn P, Abreu BC, Ottenbacher KJ. The effects of exercise training on elderly persons with cognitive impairment and dementia: a meta-analysis. Arch Phys Med Rehabil 2004;85:1694-704. Objective To determine by meta-analysis whether physical exercises are beneficial for people with dementia and related cognitive impairments. Data sources Published articles and nonpublished manuscripts from 1970 to 2003 were identified by using electronic and manual searches. Key search words included exercise, rehabilitation, activities of daily living, dementia, Alzheimer's disease, aged, and geriatrics. Study selection Reviewed studies were limited to randomized trials evaluating exercise in persons 65 years of age or older with cognitive impairment. Studies included quantitative results (means, standard deviations, t tests, F tests) for physical fitness, physical functioning, cognition, or behavior outcomes. Data extraction One reviewer extracted data on study characteristics and findings. Selected articles were evaluated for methodologic quality by 2 raters. Data synthesis A total of 2020 subjects participated in the 30 trials that met the inclusion criteria. Summary effects were computed using a fixed effects (Hedge's gi) model. Significant summary effect sizes (ES) were found for strength (ES=.75; 95% confidence interval [CI], .58-.92), physical fitness (ES=.69; 95% CI, .58-.80), functional performance (ES=.59; 95% CI, .43-.76), cognitive performance (ES=.57; 95% CI, 0.43-1.17), and behavior (ES=.54; 95% CI, .36-.72). The overall mean ES between exercise and nonexercise groups for all outcomes was .62 (95% CI, .55-.70). Conclusions Exercise training increases fitness, physical function, cognitive function, and positive behavior in people with dementia and related cognitive impairments.

KW - Alzheimer disease

KW - Dementia

KW - Exercise

KW - Meta-Analysis

KW - Rehabilitation

UR - http://www.scopus.com/inward/record.url?scp=5344237365&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=5344237365&partnerID=8YFLogxK

U2 - 10.1016/j.apmr.2004.03.019

DO - 10.1016/j.apmr.2004.03.019

M3 - Article

VL - 85

SP - 1694

EP - 1704

JO - Archives of Physical Medicine and Rehabilitation

JF - Archives of Physical Medicine and Rehabilitation

SN - 0003-9993

IS - 10

ER -