The fate of small renal masses, less then 1 cm size: Outcome study

Erich K. Lang, Amer Hanano, Ernest Rudman, Raju Thomas, Leann Myers, Quan Nguyen, Richard J. Macchia

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Purpose: We evaluated the outcome and etiologies of small renal masses (less than 1 cm in size) discovered incidentally on 2 consecutive CTs that investigated nonurologic abdominal complaints. Materials and Methods: A retrospective search for incidentally discovered small renal masses, less then 1 cm in size, was carried out in the files of 6 major US medical centers. 4822 such lesions had been reported over a 12 year period. A search of these patients' records revealed 1082 subsequent new CTs for non urologic complaints, allowing the assessment of the fate of the masses. Lesions enlarging, of ambivalent contour or enhancement were examined by a third multiphasic MDCT. The findings were interpreted by 2 blinded radiologists. Results: Six hundred and four masses could no longer be identified, 231 were significantly smaller, 113 unchanged in size and 134 larger. Of the disappearing lesions 448 were located in the medulla, 94 both in medulla and cortex and 62 in cortex. Multiphasic MDCTs obtained in 308 masses enlarging, unchanged in size or of ambivalent appearance, revealed 7 neoplasms, 45 inflammatory lesions, 8 abscesses and 62 renal medullary necrosis. Concurrent antibiotic therapy of GI conditions may have caused some of the 496 lesions to disappear. Conclusion: It is questionable whether the small number of malignant neoplasms (0.4%), inflammatory lesions (5%) and renal medullary necrosis (6%) justify routine follow-up CTs and exposure to radiation. The delay in intervention in neoplastic lesions probably didn't influence tumor-free survival potential and clinical symptoms would soon have revealed inflammatory conditions. With exception of ambivalent lesions, clinical surveillance appears adequate.

Original languageEnglish (US)
Pages (from-to)40-47
Number of pages8
JournalInternational Braz J Urol
Volume38
Issue number1
DOIs
StatePublished - 2012
Externally publishedYes

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Kidney Papillary Necrosis
Outcome Assessment (Health Care)
Kidney
Neoplasms
Abscess
Anti-Bacterial Agents
Survival
Therapeutics

Keywords

  • kidney
  • Neoplasms
  • Outcome assessment

ASJC Scopus subject areas

  • Urology

Cite this

Lang, E. K., Hanano, A., Rudman, E., Thomas, R., Myers, L., Nguyen, Q., & Macchia, R. J. (2012). The fate of small renal masses, less then 1 cm size: Outcome study. International Braz J Urol, 38(1), 40-47. https://doi.org/10.1590/S1677-55382012000100006

The fate of small renal masses, less then 1 cm size : Outcome study. / Lang, Erich K.; Hanano, Amer; Rudman, Ernest; Thomas, Raju; Myers, Leann; Nguyen, Quan; Macchia, Richard J.

In: International Braz J Urol, Vol. 38, No. 1, 2012, p. 40-47.

Research output: Contribution to journalArticle

Lang, EK, Hanano, A, Rudman, E, Thomas, R, Myers, L, Nguyen, Q & Macchia, RJ 2012, 'The fate of small renal masses, less then 1 cm size: Outcome study', International Braz J Urol, vol. 38, no. 1, pp. 40-47. https://doi.org/10.1590/S1677-55382012000100006
Lang, Erich K. ; Hanano, Amer ; Rudman, Ernest ; Thomas, Raju ; Myers, Leann ; Nguyen, Quan ; Macchia, Richard J. / The fate of small renal masses, less then 1 cm size : Outcome study. In: International Braz J Urol. 2012 ; Vol. 38, No. 1. pp. 40-47.
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