The gut: a key organ following injury and infection

W. W. Souba; R. M. Salloum; T. R. Austgen; M. K. Chen; V. S. Klimberg; D. A. Plumley; A. J. Pacitti; H. S. Sitren; E. M. Copeland

The gut: a key organ following injury and infection

W. W. Souba, R. M. Salloum, T. R. Austgen, M. K. Chen, V. S. Klimberg, D. A. Plumley, A. J. Pacitti, H. S. Sitren, E. M. Copeland

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

The intestinal tract plays a key role in the body's response to injury and infection, both as a barrier to poisons and as a substrate processing station for the liver and other organs. Like the kidneys, heart, lungs, and liver, the gut is susceptible to dysfunction and possibly failure in certain critically ill patients. This failure is far more complex than simple ileus from bowel inactivity and disuse. Optimal support for the intestinal tract during catabolic states requires provision of appropriate nutrition, support of other organs, aggressive management of wounds, and possibly the use of newer growth factors which may have trophic effects on the gut mucosa. Enteral nutrition is currently the preferred method of feeding and should be instituted whenever feasible.

Original language	English (US)
Pages (from-to)	7-14
Number of pages	8
Journal	Rivista Italiana di Nutrizione Parenterale ed Enterale
Volume	9
Issue number	1
State	Published - 1991
Externally published	Yes

ASJC Scopus subject areas

Critical Care and Intensive Care Medicine
Food Science
Nutrition and Dietetics
Anatomy

Cite this

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abstract = "The intestinal tract plays a key role in the body's response to injury and infection, both as a barrier to poisons and as a substrate processing station for the liver and other organs. Like the kidneys, heart, lungs, and liver, the gut is susceptible to dysfunction and possibly failure in certain critically ill patients. This failure is far more complex than simple ileus from bowel inactivity and disuse. Optimal support for the intestinal tract during catabolic states requires provision of appropriate nutrition, support of other organs, aggressive management of wounds, and possibly the use of newer growth factors which may have trophic effects on the gut mucosa. Enteral nutrition is currently the preferred method of feeding and should be instituted whenever feasible.",

author = "Souba, {W. W.} and Salloum, {R. M.} and Austgen, {T. R.} and Chen, {M. K.} and Klimberg, {V. S.} and Plumley, {D. A.} and Pacitti, {A. J.} and Sitren, {H. S.} and Copeland, {E. M.}",

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T2 - a key organ following injury and infection

AU - Souba, W. W.

AU - Salloum, R. M.

AU - Austgen, T. R.

AU - Chen, M. K.

AU - Klimberg, V. S.

AU - Plumley, D. A.

AU - Pacitti, A. J.

AU - Sitren, H. S.

AU - Copeland, E. M.

PY - 1991

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AB - The intestinal tract plays a key role in the body's response to injury and infection, both as a barrier to poisons and as a substrate processing station for the liver and other organs. Like the kidneys, heart, lungs, and liver, the gut is susceptible to dysfunction and possibly failure in certain critically ill patients. This failure is far more complex than simple ileus from bowel inactivity and disuse. Optimal support for the intestinal tract during catabolic states requires provision of appropriate nutrition, support of other organs, aggressive management of wounds, and possibly the use of newer growth factors which may have trophic effects on the gut mucosa. Enteral nutrition is currently the preferred method of feeding and should be instituted whenever feasible.

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The gut: a key organ following injury and infection

Abstract

ASJC Scopus subject areas

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