The histopathologic features of lithium-associated thyroiditis

Theodosios Kontozoglou; Nobby Mambo

doi:10.1016/S0046-8177(83)80150-6

The histopathologic features of lithium-associated thyroiditis

Theodosios Kontozoglou
, Nobby Mambo

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

The case of a 62-year-old woman with lithium-associated thyroiditis is presented. Lithium can produce goiters associated with hypothyroidism and, less commonly, hyperthyroidism and euthyroidism. The characteristic histopathologic features of the affected thyroid gland included fibrosis, lymphoid follicles with atrophy, and hyperplasia of thyroid follicles. The pathogenetic mechanism appears to be immunologic, with lithium acting as a haptene with a thyroid antigen to induce an "autoimmune" type of thyroiditis.

Original language	English (US)
Pages (from-to)	737-739
Number of pages	3
Journal	Human Pathology
Volume	14
Issue number	8
DOIs	https://doi.org/10.1016/S0046-8177(83)80150-6
State	Published - Aug 1983
Externally published	Yes

ASJC Scopus subject areas

Pathology and Forensic Medicine

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10.1016/S0046-8177(83)80150-6

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AU - Mambo, Nobby

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AB - The case of a 62-year-old woman with lithium-associated thyroiditis is presented. Lithium can produce goiters associated with hypothyroidism and, less commonly, hyperthyroidism and euthyroidism. The characteristic histopathologic features of the affected thyroid gland included fibrosis, lymphoid follicles with atrophy, and hyperplasia of thyroid follicles. The pathogenetic mechanism appears to be immunologic, with lithium acting as a haptene with a thyroid antigen to induce an "autoimmune" type of thyroiditis.

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U2 - 10.1016/S0046-8177(83)80150-6

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The histopathologic features of lithium-associated thyroiditis

Abstract

ASJC Scopus subject areas

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