Appendicitis was induced in six New Zealand white rabbits. The appendices from these animals had significantly higher spin-lattice relaxation times, T1, as determined in vitro by nuclear magnetic resonance (NMR) (10 controls vs 6 experimentals, 413 ± 23 vs 455 ± 41, X ± SD, P < (0.02). T1 correlated significantly with the water content of the appendiceal tissue (P < 0.001). These findings suggest that in vivo NMR imaging techniques weighted on T1 might be able to identify human appendicitis noninvasively by detecting localized edema.
ASJC Scopus subject areas