The identification of experimentally induced appendicitis using in vitro nuclear magnetic resonance

Danny O. Jacobs; John R. Clarke; R. G. Settle; A. K. Sachdeva; James E. Wheeler; Scott O. Trerotola; Gerald L. Wolf; John L. Rombeau

doi:10.1016/0022-4804(85)90156-8

The identification of experimentally induced appendicitis using in vitro nuclear magnetic resonance

Danny O. Jacobs
, John R. Clarke
, R. G. Settle
, A. K. Sachdeva
, James E. Wheeler
, Scott O. Trerotola
, Gerald L. Wolf
, John L. Rombeau

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Appendicitis was induced in six New Zealand white rabbits. The appendices from these animals had significantly higher spin-lattice relaxation times, T1, as determined in vitro by nuclear magnetic resonance (NMR) (10 controls vs 6 experimentals, 413 ± 23 vs 455 ± 41, X ± SD, P < (0.02). T1 correlated significantly with the water content of the appendiceal tissue (P < 0.001). These findings suggest that in vivo NMR imaging techniques weighted on T1 might be able to identify human appendicitis noninvasively by detecting localized edema.

Original language	English (US)
Pages (from-to)	16-24
Number of pages	9
Journal	Journal of Surgical Research
Volume	39
Issue number	1
DOIs	https://doi.org/10.1016/0022-4804(85)90156-8
State	Published - Jul 1985
Externally published	Yes

ASJC Scopus subject areas

Surgery

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@article{9e037a32d46b4a19ade07ca75d9dae3e,

title = "The identification of experimentally induced appendicitis using in vitro nuclear magnetic resonance",

abstract = "Appendicitis was induced in six New Zealand white rabbits. The appendices from these animals had significantly higher spin-lattice relaxation times, T1, as determined in vitro by nuclear magnetic resonance (NMR) (10 controls vs 6 experimentals, 413 ± 23 vs 455 ± 41, X ± SD, P < (0.02). T1 correlated significantly with the water content of the appendiceal tissue (P < 0.001). These findings suggest that in vivo NMR imaging techniques weighted on T1 might be able to identify human appendicitis noninvasively by detecting localized edema.",

author = "Jacobs, \{Danny O.\} and Clarke, \{John R.\} and Settle, \{R. G.\} and Sachdeva, \{A. K.\} and Wheeler, \{James E.\} and Trerotola, \{Scott O.\} and Wolf, \{Gerald L.\} and Rombeau, \{John L.\}",

year = "1985",

month = jul,

doi = "10.1016/0022-4804(85)90156-8",

language = "English (US)",

volume = "39",

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T1 - The identification of experimentally induced appendicitis using in vitro nuclear magnetic resonance

AU - Jacobs, Danny O.

AU - Clarke, John R.

AU - Settle, R. G.

AU - Sachdeva, A. K.

AU - Wheeler, James E.

AU - Trerotola, Scott O.

AU - Wolf, Gerald L.

AU - Rombeau, John L.

PY - 1985/7

Y1 - 1985/7

N2 - Appendicitis was induced in six New Zealand white rabbits. The appendices from these animals had significantly higher spin-lattice relaxation times, T1, as determined in vitro by nuclear magnetic resonance (NMR) (10 controls vs 6 experimentals, 413 ± 23 vs 455 ± 41, X ± SD, P < (0.02). T1 correlated significantly with the water content of the appendiceal tissue (P < 0.001). These findings suggest that in vivo NMR imaging techniques weighted on T1 might be able to identify human appendicitis noninvasively by detecting localized edema.

AB - Appendicitis was induced in six New Zealand white rabbits. The appendices from these animals had significantly higher spin-lattice relaxation times, T1, as determined in vitro by nuclear magnetic resonance (NMR) (10 controls vs 6 experimentals, 413 ± 23 vs 455 ± 41, X ± SD, P < (0.02). T1 correlated significantly with the water content of the appendiceal tissue (P < 0.001). These findings suggest that in vivo NMR imaging techniques weighted on T1 might be able to identify human appendicitis noninvasively by detecting localized edema.

UR - https://www.scopus.com/pages/publications/0022344999

UR - https://www.scopus.com/pages/publications/0022344999#tab=citedBy

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AN - SCOPUS:0022344999

SN - 0022-4804

VL - 39

SP - 16

EP - 24

JO - Journal of Surgical Research

JF - Journal of Surgical Research

IS - 1

ER -

The identification of experimentally induced appendicitis using in vitro nuclear magnetic resonance

Abstract

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