THE IMMUNE SYSTEM AND INFECTIOUS DISEASES

J. Holmgren, R. M. Goldblum

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Abstract

Enteric gram negative bacteria have been found to posses antigens which cross react wih blood group antigens and with the Forssman antigen. Extensive studies of these antigenic relationships have provided a molecular structural basis for immunological cross reactivity. They have also raised interest in the potential medical significance of such cross reacting antigens in microbes and man as inducers of natural antibodies, protective immunity or autoimmune reactions. A role of enteric bacterial antigen in the pathogenesis of autoimmune disease has been further suggested by the finding that the autoantibodies in patients wih ulcerative colitis cross react with the so called common antigen of Enterobacteriaceae. This paper reviews recent data showing an antigenic relationsip between kidney tissue and certain strains of Escherichia coli, and discusses their potential significance in the renal scarring which occasionally develops as a sequela of urinary tract infections.

Original languageEnglish (US)
Title of host publicationINTERNAT.CONV.IMMUNOL., KARGER
Pages263-271
Number of pages9
Volume4
StatePublished - 1975
Externally publishedYes

Fingerprint

Immune System Diseases
Communicable Diseases
Enterobacteriaceae
Antigens
Forssman Antigen
Bacterial Antigens
Kidney
Blood Group Antigens
Gram-Negative Bacteria
Ulcerative Colitis
Urinary Tract Infections
Autoantibodies
Autoimmune Diseases
Cicatrix
Immunity
Escherichia coli
Antibodies

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Holmgren, J., & Goldblum, R. M. (1975). THE IMMUNE SYSTEM AND INFECTIOUS DISEASES. In INTERNAT.CONV.IMMUNOL., KARGER (Vol. 4, pp. 263-271)

THE IMMUNE SYSTEM AND INFECTIOUS DISEASES. / Holmgren, J.; Goldblum, R. M.

INTERNAT.CONV.IMMUNOL., KARGER. Vol. 4 1975. p. 263-271.

Research output: Chapter in Book/Report/Conference proceedingChapter

Holmgren, J & Goldblum, RM 1975, THE IMMUNE SYSTEM AND INFECTIOUS DISEASES. in INTERNAT.CONV.IMMUNOL., KARGER. vol. 4, pp. 263-271.
Holmgren J, Goldblum RM. THE IMMUNE SYSTEM AND INFECTIOUS DISEASES. In INTERNAT.CONV.IMMUNOL., KARGER. Vol. 4. 1975. p. 263-271
Holmgren, J. ; Goldblum, R. M. / THE IMMUNE SYSTEM AND INFECTIOUS DISEASES. INTERNAT.CONV.IMMUNOL., KARGER. Vol. 4 1975. pp. 263-271
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