The incubation period of hantavirus pulmonary syndrome

J. C. Young, G. R. Hansen, T. K. Graves, M. P. Deasy, J. G. Humphreys, C. L. Fritz, K. L. Gorham, A. S. Khan, T. G. Ksiazek, K. B. Metzger, C. J. Peters

Research output: Contribution to journalArticlepeer-review

74 Scopus citations


In 1993 Sin Nombre virus was recognized as the cause of hantavirus pulmonary syndrome (HPS) and the deer mouse (Peromyscus manicularus) was identified as the reservoir host. Surveillance by the Centers for Disease Control and Prevention and state health departments includes investigation to determine the likely site(s) and activities that led to infection, an environmental assessment of the home and workplace, and possibly rodent trappings ar these sites. As of December 31, 1998, there were 200 confirmed cases from 30 states (43% case-fatality ratio), The national HPS case registry was examined to determine the incubation period of HPS. Review of 11 case-patients with well-defined and isolated exposure to rodents suggests that the incubation period of HPS is 9 to 33 days, with a median of 14-17 days, Case investigations allow a better understanding of the incubation rime of HPS and may define highrisk behaviors that can be targeted for intervention.

Original languageEnglish (US)
Pages (from-to)714-717
Number of pages4
JournalAmerican Journal of Tropical Medicine and Hygiene
Issue number6
StatePublished - 2000
Externally publishedYes

ASJC Scopus subject areas

  • Infectious Diseases
  • Virology
  • Parasitology


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