TY - JOUR
T1 - The Influence of Obesity on Treatment and Outcome of Severely Burned Patients
AU - Tapking, Christian
AU - Houschyar, Khosrow S.
AU - Rontoyanni, Victoria G.
AU - Hundeshagen, Gabriel
AU - Kowalewski, Karl Friedrich
AU - Hirche, Christoph
AU - Popp, Daniel
AU - Wolf, Steven E.
AU - Herndon, David N.
AU - Branski, Ludwik K.
N1 - Publisher Copyright:
© 2019 The Author(s) 2019. Published by Oxford University Press on behalf of the American Burn Association. All rights reserved.
PY - 2019/10/16
Y1 - 2019/10/16
N2 - Obesity and the related medical, social, and economic impacts are relevant multifactorial and chronic conditions that also have a meaningful impact on outcomes following a severe injury, including burns. In addition to burn-specific difficulties, such as adequate hypermetabolic response, fluid resuscitation, and early wound coverage, obese patients also present with common comorbidities, such as arterial hypertension, diabetes mellitus, or nonalcoholic fatty liver disease. In addition, the pathophysiologic response to severe burns can be enhanced. Besides the increased morbidity and mortality compared to burn patients with normal weight, obese patients present a challenge in fluid resuscitation, perioperative management, and difficulties in wound healing. The present work is an in-depth review of the current understanding of the influence of obesity on the management and outcome of severe burns.
AB - Obesity and the related medical, social, and economic impacts are relevant multifactorial and chronic conditions that also have a meaningful impact on outcomes following a severe injury, including burns. In addition to burn-specific difficulties, such as adequate hypermetabolic response, fluid resuscitation, and early wound coverage, obese patients also present with common comorbidities, such as arterial hypertension, diabetes mellitus, or nonalcoholic fatty liver disease. In addition, the pathophysiologic response to severe burns can be enhanced. Besides the increased morbidity and mortality compared to burn patients with normal weight, obese patients present a challenge in fluid resuscitation, perioperative management, and difficulties in wound healing. The present work is an in-depth review of the current understanding of the influence of obesity on the management and outcome of severe burns.
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U2 - 10.1093/jbcr/irz115
DO - 10.1093/jbcr/irz115
M3 - Article
C2 - 31294797
AN - SCOPUS:85073582522
SN - 1559-047X
VL - 40
SP - 996
EP - 1008
JO - Journal of Burn Care and Research
JF - Journal of Burn Care and Research
IS - 6
ER -