The medical treatment for autoimmune hepatitis through corticosteroid to new immunosuppressive agents: A concise review

Roger D. Soloway, Alexander T. Hewlett

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

The treatment of autoimmune hepatitis is evolving as the natural history of the disease and newer agents become available. This concise review will outline the various treatment options in these patients. Treatment with current corticosteroids and azathioprine works in most patients but issues of intolerance and incomplete response arise. These situations led to the investigation of newer immunosupressants including mycophenolate mofetil, budesonide cyclosporine, tacrolimus and ursodeoxycholic acid. The newer agents have been studied in small patient numbers so they are not first-line treatment yet but do have a clear role in those patients with intolerance of incomplete response to standard corticosteroids and azathioprine.

Original languageEnglish (US)
Pages (from-to)204-207
Number of pages4
JournalAnnals of Hepatology
Volume6
Issue number4
DOIs
StatePublished - 2007

Keywords

  • Azathioprine
  • Mycophenolate mofetil
  • Remission
  • Ursodeoxycholic acid

ASJC Scopus subject areas

  • Hepatology

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