TY - JOUR
T1 - The microbiome modulates arbovirus transmission in mosquitoes
AU - Hegde, Shivanand
AU - Rasgon, Jason L.
AU - Hughes, Grant L.
N1 - Funding Information:
This work has been supported by a University of Texas Rising Star Award and Brown Foundation grant to GLH and by NIH/NIAID grants R21AI111175 , R21AI088311 , R56AI116636 and R01AI067371 to JLR.
PY - 2015/12/15
Y1 - 2015/12/15
N2 - Mosquito-transmitted arthropod-borne viruses (arboviruses) such as dengue virus, chikungunya virus, and West Nile virus constitute a major public health burden and are increasing in severity and frequency worldwide. The microbiota associated with mosquitoes (comprised of viruses, bacteria, fungi and protozoa) can profoundly influence many host phenotypes including vector competence, which can either be enhanced or suppressed. Thus, the tripartite interactions between the mosquito vector, its microbiota and the pathogens they transmit offer novel possibilities to control arthropod-borne diseases.
AB - Mosquito-transmitted arthropod-borne viruses (arboviruses) such as dengue virus, chikungunya virus, and West Nile virus constitute a major public health burden and are increasing in severity and frequency worldwide. The microbiota associated with mosquitoes (comprised of viruses, bacteria, fungi and protozoa) can profoundly influence many host phenotypes including vector competence, which can either be enhanced or suppressed. Thus, the tripartite interactions between the mosquito vector, its microbiota and the pathogens they transmit offer novel possibilities to control arthropod-borne diseases.
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U2 - 10.1016/j.coviro.2015.08.011
DO - 10.1016/j.coviro.2015.08.011
M3 - Review article
C2 - 26363996
AN - SCOPUS:84941553728
SN - 1879-6257
VL - 15
SP - 97
EP - 102
JO - Current Opinion in Virology
JF - Current Opinion in Virology
ER -