The National NeuroAIDS Tissue Consortium: A new paradigm in brain banking with an emphasis on infectious disease

S. Morgello, B. B. Gelman, P. B. Kozlowski, H. V. Vinters, E. Masliah, M. Cornford, W. Cavert, C. Marra, I. Grant, E. J. Singer

Research output: Contribution to journalArticle

97 Scopus citations

Abstract

The National NeuroAIDS Tissue Consortium (NNTC) was founded in 1998, in response to the scientific need for well-characterized central nervous system (CNS) and peripheral nervous system (PNS) tissues and fluids from HIV-infected individuals. In addition to performing the routine functions of non-transplant anatomic tissue banks, the Consortium offers a unique model for the integration of independent research entities in order to provide well-characterized tissues and fluids for the international research community. Herein, we describe the structure of the Consortium, pointing out the inherent strengths of linking together multiple independent sites for the purpose of banking HIV-infected nervous system tissues. We describe the neuropathology protocol that was adopted and successfully implemented at the four participating banks of the Consortium.

Original languageEnglish (US)
Pages (from-to)326-335
Number of pages10
JournalNeuropathology and Applied Neurobiology
Volume27
Issue number4
DOIs
StatePublished - Aug 29 2001

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Keywords

  • AIDS
  • Brain bank
  • HIV

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Neurology
  • Clinical Neurology
  • Physiology (medical)

Cite this

Morgello, S., Gelman, B. B., Kozlowski, P. B., Vinters, H. V., Masliah, E., Cornford, M., Cavert, W., Marra, C., Grant, I., & Singer, E. J. (2001). The National NeuroAIDS Tissue Consortium: A new paradigm in brain banking with an emphasis on infectious disease. Neuropathology and Applied Neurobiology, 27(4), 326-335. https://doi.org/10.1046/j.0305-1846.2001.00334.x