The obstetric and neonatal implications of a low value on the 50-g glucose screening test

Kimberly K. Ma, Lisa Mele, Mark B. Landon, Catherine Y. Spong, Susan M. Ramin, Brian Casey, Ronald J. Wapner, Michael W. Varner, Dwight J. Rouse, John M. Thorp, Anthony Sciscione, Patrick Catalano, Margaret Harper, George Saade, Steve N. Caritis, Yoram Sorokin, Alan M. Peaceman

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objective To assess the relationship between a low 50-g 1-hour glucose loading test (GLT) and maternal and neonatal outcomes in women without diabetes. Study Design This was a secondary analysis of a multicenter observational cohort from a randomized trial of treatment for mild gestational diabetes. Maternal and neonatal outcomes were compared between women with GLT values < 90 mg/dL and those with results 90 to 119 mg/dL. Results Of 436 enrolled women, 297 (68.1%) had a GLT result of 90 to 119 mg/dL and 139 (31.9%) had a result of < 90 mg/dL. There was a lower incidence of neonatal hypoglycemia in those with a GLT < 90 mg/dL (5.7% versus 16.5%, p = 0.006). Other outcomes were not associated with test results. Conclusion A GLT result < 90 mg/dL compared with 90 to 119 mg/dL is associated with a lower risk of neonatal hypoglycemia, but no other significant findings.

Original languageEnglish (US)
Pages (from-to)715-721
Number of pages7
JournalAmerican Journal of Perinatology
Volume30
Issue number9
DOIs
StatePublished - 2013

Fingerprint

Obstetrics
Glucose
Hypoglycemia
Mothers
Gestational Diabetes
Incidence
Therapeutics

Keywords

  • low glucose screening test
  • neonatal hypoglycemia

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

Ma, K. K., Mele, L., Landon, M. B., Spong, C. Y., Ramin, S. M., Casey, B., ... Peaceman, A. M. (2013). The obstetric and neonatal implications of a low value on the 50-g glucose screening test. American Journal of Perinatology, 30(9), 715-721. https://doi.org/10.1055/s-0032-1331027

The obstetric and neonatal implications of a low value on the 50-g glucose screening test. / Ma, Kimberly K.; Mele, Lisa; Landon, Mark B.; Spong, Catherine Y.; Ramin, Susan M.; Casey, Brian; Wapner, Ronald J.; Varner, Michael W.; Rouse, Dwight J.; Thorp, John M.; Sciscione, Anthony; Catalano, Patrick; Harper, Margaret; Saade, George; Caritis, Steve N.; Sorokin, Yoram; Peaceman, Alan M.

In: American Journal of Perinatology, Vol. 30, No. 9, 2013, p. 715-721.

Research output: Contribution to journalArticle

Ma, KK, Mele, L, Landon, MB, Spong, CY, Ramin, SM, Casey, B, Wapner, RJ, Varner, MW, Rouse, DJ, Thorp, JM, Sciscione, A, Catalano, P, Harper, M, Saade, G, Caritis, SN, Sorokin, Y & Peaceman, AM 2013, 'The obstetric and neonatal implications of a low value on the 50-g glucose screening test', American Journal of Perinatology, vol. 30, no. 9, pp. 715-721. https://doi.org/10.1055/s-0032-1331027
Ma, Kimberly K. ; Mele, Lisa ; Landon, Mark B. ; Spong, Catherine Y. ; Ramin, Susan M. ; Casey, Brian ; Wapner, Ronald J. ; Varner, Michael W. ; Rouse, Dwight J. ; Thorp, John M. ; Sciscione, Anthony ; Catalano, Patrick ; Harper, Margaret ; Saade, George ; Caritis, Steve N. ; Sorokin, Yoram ; Peaceman, Alan M. / The obstetric and neonatal implications of a low value on the 50-g glucose screening test. In: American Journal of Perinatology. 2013 ; Vol. 30, No. 9. pp. 715-721.
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AU - Casey, Brian

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AU - Sciscione, Anthony

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AU - Saade, George

AU - Caritis, Steve N.

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AB - Objective To assess the relationship between a low 50-g 1-hour glucose loading test (GLT) and maternal and neonatal outcomes in women without diabetes. Study Design This was a secondary analysis of a multicenter observational cohort from a randomized trial of treatment for mild gestational diabetes. Maternal and neonatal outcomes were compared between women with GLT values < 90 mg/dL and those with results 90 to 119 mg/dL. Results Of 436 enrolled women, 297 (68.1%) had a GLT result of 90 to 119 mg/dL and 139 (31.9%) had a result of < 90 mg/dL. There was a lower incidence of neonatal hypoglycemia in those with a GLT < 90 mg/dL (5.7% versus 16.5%, p = 0.006). Other outcomes were not associated with test results. Conclusion A GLT result < 90 mg/dL compared with 90 to 119 mg/dL is associated with a lower risk of neonatal hypoglycemia, but no other significant findings.

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