The PARP inhibitor olaparib exerts beneficial effects in mice subjected to cecal ligature and puncture and in cells subjected to oxidative stress without impairing DNA integrity: A potential opportunity for repurposing a clinically used oncological drug for the experimental therapy of sepsis

Akbar Ahmad, Juliana de Camargo Vieira, Aline Haas de Mello, Thais Martins de Lima, Suely Kubo Ariga, Denise Frediani Barbeiro, Hermes Vieira Barbeiro, Bartosz Szczesny, Gábor Törö, Nadiya Druzhyna, Elisa B. Randi, Michela Marcatti, Tracy Toliver-Kinsky, András Kiss, Lucas Liaudet, Reinaldo Salomao, Francisco Garcia Soriano, Csaba Szabo

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Medicine and Dentistry

Pharmacology, Toxicology and Pharmaceutical Science