The pediatric Chiari I malformation

A review

R. Shane Tubbs, Michael J. Lyerly, Marios Loukas, Mohammadali Mohajel Shoja, W. Jerry Oakes

Research output: Contribution to journalReview article

108 Citations (Scopus)

Abstract

Background: Both the diagnosis and treatment regimens for the Chiari I malformation (CIM) are varied and controversial. The present paper analyzes the literature regarding this form of hindbrain herniation in regard to definition, anatomy, pathobiology, symptoms, findings, treatment, and outcomes. Discussions: Appropriate literature germane tothe CIM is reviewed and discussed. There is variation in the reported anatomy, outcome, and treatment for children with CIM. Based on the literature, most patients have preoperative symptoms or findings (e.g., syringomyelia) improve no matter what surgical technique is utilized. However, standardized treatment paradigms based on randomized controlled studies are still necessary to elucidate the optimal selection and treatment criteria.

Original languageEnglish (US)
Pages (from-to)1239-1250
Number of pages12
JournalChild's Nervous System
Volume23
Issue number11
DOIs
StatePublished - Nov 1 2007
Externally publishedYes

Fingerprint

Pediatrics
Anatomy
Syringomyelia
Rhombencephalon
Patient Selection
Therapeutics

Keywords

  • Hindbrain hernia
  • Neurosurgery
  • Tonsillar ectopia

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Cite this

Tubbs, R. S., Lyerly, M. J., Loukas, M., Mohajel Shoja, M., & Oakes, W. J. (2007). The pediatric Chiari I malformation: A review. Child's Nervous System, 23(11), 1239-1250. https://doi.org/10.1007/s00381-007-0428-0

The pediatric Chiari I malformation : A review. / Tubbs, R. Shane; Lyerly, Michael J.; Loukas, Marios; Mohajel Shoja, Mohammadali; Oakes, W. Jerry.

In: Child's Nervous System, Vol. 23, No. 11, 01.11.2007, p. 1239-1250.

Research output: Contribution to journalReview article

Tubbs, RS, Lyerly, MJ, Loukas, M, Mohajel Shoja, M & Oakes, WJ 2007, 'The pediatric Chiari I malformation: A review', Child's Nervous System, vol. 23, no. 11, pp. 1239-1250. https://doi.org/10.1007/s00381-007-0428-0
Tubbs RS, Lyerly MJ, Loukas M, Mohajel Shoja M, Oakes WJ. The pediatric Chiari I malformation: A review. Child's Nervous System. 2007 Nov 1;23(11):1239-1250. https://doi.org/10.1007/s00381-007-0428-0
Tubbs, R. Shane ; Lyerly, Michael J. ; Loukas, Marios ; Mohajel Shoja, Mohammadali ; Oakes, W. Jerry. / The pediatric Chiari I malformation : A review. In: Child's Nervous System. 2007 ; Vol. 23, No. 11. pp. 1239-1250.
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