The physical therapy clinical research network (PTClinResNet) methods, efficacy, and benefits of a rehabilitation research network

Carolee Winstein, Patricia Pate, Tingting Ge, Carolyn Ervin, James Baurley, Katherine J. Sullivan, Samantha J. Underwood, Eileen G. Fowler, Sara Mulroy, David A. Brown, Kornelia Kulig, James Gordon, Stanley P. Azen

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


This article describes the vision, methods, and implementation strategies used in building the infrastructure for PTClinResNet, a clinical research network designed to assess outcomes for health-related mobility associated with evidence-based physical therapy interventions across and within four different disability groups. Specific aims were to (1) create the infrastructure necessary to develop and sustain clinical trials research in rehabilitation, (2) generate evidence to evaluate the efficacy of resistance exercise-based physical interventions designed to improve muscle performance and movement skills, and (3) provide education and training opportunities for present and future clinician-researchers and for the rehabilitation community at-large in its support of evidence-based practice. We present the network's infrastructure, development, and several examples that highlight the benefits of a clinical research network. We suggest that the network structure is ideal for building research capacity and fostering multisite, multiinvestigator clinical research projects designed to generate evidence for the efficacy of rehabilitation interventions.

Original languageEnglish (US)
Pages (from-to)937-950
Number of pages14
JournalAmerican Journal of Physical Medicine and Rehabilitation
Issue number11
StatePublished - Nov 2008
Externally publishedYes


  • Biomedical informatics
  • Disablement model
  • Medical rehabilitation
  • Multisite clinical trials
  • Outcomes research
  • Physical therapy

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation


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