The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation

Biochemistry, Genetics and Molecular Biology

• Proteomics 100%
• Proinflammatory Cytokine 100%
• Cell Cycle Regulation 100%
• Lysine 50%
• interferon 50%
• Tumor Suppressor Protein 50%
• Monospecific Antibody 50%
• Eicosanoid Receptor 50%
• Enzyme 50%
• Mass Spectrometry 50%
• Autophagy 50%
• P53 50%
• Ubiquitin 50%
• Tumor Necrosis Factor 50%
• Interferon 50%
• Histone Deacetylase 50%
• Isopeptide Bond 50%
• Ubiquitin-Activating Enzyme 50%
• UBA1 50%
• Degradome 50%

Keyphrases

• Proteomic Analysis 100%
• FAT10 100%
• SQSTM1 100%
• FAT10ylation 100%
• Proteasomal Degradation 21%
• Inflammatory Cytokines 14%
• Interacting Proteins 14%
• Apoptosis 7%
• Specific Antibodies 7%
• Apoptosis Induction 7%
• Mass Spectrometry 7%
• Tumor Necrosis Factor-α 7%
• Autophagy 7%
• Tumor Protein p53 (TP53) 7%
• Ubiquitin-like 7%
• Lysine 7%
• Interferon-α (IFN-α) 7%
• Endogenous Substrates 7%
• Deubiquitinating Enzyme 7%
• NF-B 7%
• Cell Cycle Control 7%
• Interaction Partner 7%
• Cell Cycle Regulation 7%
• In Cis 7%
• Isopeptide Bond 7%
• One Percent 7%
• Conjugating Enzyme 7%
• Histone Deacetylase 6 (HDAC6) 7%
• Functional Pathways 7%
• UBA6 7%
• Degradome 7%
• UBE1 7%
• UBA1 7%
• P62 Bodies 7%
• USE1 7%