The relationships among acculturation, body mass index, depression, and interleukin 1-receptor antagonist in hispanic pregnant women

R. Jeanne Ruiz, Raymond P. Stowe, Elizabeth Goluszko, Michele C. Clark, Alai Tan

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Objective: The purpose of this study was to determine relationships between acculturation, body mass index (BMI), and depressive symptoms with the Interleukin 1-mediated inflammatory response marker IL-1RA in pregnant Hispanic women at 22-24 weeks gestation. Design: An observational, prospective design with data collected at 22-24 weeks gestation. Setting: Public prenatal health clinics and private physician practices in central and south Texas serving low-income women. Main Outcome Measures: Body mass index (BMI), depression scores on the Center for Epidemiological Studies of Depression (CES-D), years in the United States, the Language Proficiency Scale (LPS), and Interleukin 1 receptor antagonist levels (IL-1 RA) Results: The longer the Hispanic women were in the United States, the higher the IL-1RA levels in plasma (F=4.55; P=.002). IL-1RA plasma levels were significantly different between low and normal BMI vs overweight and obese categories of BMI (F=8.54; P<.001). IL-1RA levels were significantly higher between those women who had high scores for depressive symptoms on the CES-D (using a cut off of 20) and those who had scores less than 20 (t-value=-2.41; P=.018). In structural equation modeling, years in the United States significantly positively predicted increased depressive symptoms, increased BMI, and increased IL-1RA levels with a good model fit. Conclusions: We found that increasing years of residency in the United States is associated with the elevated inflammatory marker IL-1RA, and increased BMI. Increased depressive symptoms also predict IL-1RA levels among Hispanic women at 22-24 weeks of pregnancy. The significance of these findings is discussed in relationship to the development and course of disease.

Original languageEnglish (US)
Pages (from-to)338-343
Number of pages6
JournalEthnicity and Disease
Volume17
Issue number2
StatePublished - Mar 2007

Fingerprint

Acculturation
Interleukin-1 Receptors
Hispanic Americans
Pregnant Women
Body Mass Index
Depression
Pregnancy
Epidemiologic Studies
Private Practice
Internship and Residency
Interleukin-1
Language
Public Health
Outcome Assessment (Health Care)
Physicians

Keywords

  • Acculturation
  • Body mass index
  • Depression
  • IL-1RA

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Medicine(all)

Cite this

The relationships among acculturation, body mass index, depression, and interleukin 1-receptor antagonist in hispanic pregnant women. / Ruiz, R. Jeanne; Stowe, Raymond P.; Goluszko, Elizabeth; Clark, Michele C.; Tan, Alai.

In: Ethnicity and Disease, Vol. 17, No. 2, 03.2007, p. 338-343.

Research output: Contribution to journalArticle

Ruiz, R. Jeanne ; Stowe, Raymond P. ; Goluszko, Elizabeth ; Clark, Michele C. ; Tan, Alai. / The relationships among acculturation, body mass index, depression, and interleukin 1-receptor antagonist in hispanic pregnant women. In: Ethnicity and Disease. 2007 ; Vol. 17, No. 2. pp. 338-343.
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