The Rickettsioses

A Practical Update

    Research output: Contribution to journalReview article

    3 Citations (Scopus)

    Abstract

    Rickettsia are small, obligately intracellular, gram-negative bacilli. They are distributed among a variety of hematophagous arthropod vectors and cause illness throughout the world. Rickettsioses present as an acute undifferentiated febrile illness and are often accompanied by headache, myalgias, and malaise. Cutaneous manifestations include rash and eschar, which both occur at varying incidence depending on the infecting species. Serology is the mainstay of diagnosis, and the indirect immunofluorescence assay is the test of choice. Reactive antibodies are seldom present during early illness, so testing should be performed on both acute-phase and convalescent-phase sera. Doxycycline is the treatment of choice.

    Original languageEnglish (US)
    Pages (from-to)213-229
    Number of pages17
    JournalInfectious Disease Clinics of North America
    Volume33
    Issue number1
    DOIs
    StatePublished - Mar 1 2019

    Fingerprint

    Arthropod Vectors
    Skin Manifestations
    Rickettsia
    Doxycycline
    Myalgia
    Serology
    Indirect Fluorescent Antibody Technique
    Exanthema
    Bacillus
    Headache
    Fever
    Antibodies
    Incidence
    Serum
    Therapeutics

    Keywords

    • Epidemic typhus
    • Murine typhus
    • Rickettsia prowazekii
    • Rickettsia rickettsii
    • Rickettsia typhi
    • Rocky mountain spotted fever
    • Spotted fever group rickettsioses
    • Vector-borne disease

    ASJC Scopus subject areas

    • Microbiology (medical)
    • Infectious Diseases

    Cite this

    The Rickettsioses : A Practical Update. / Blanton, Lucas.

    In: Infectious Disease Clinics of North America, Vol. 33, No. 1, 01.03.2019, p. 213-229.

    Research output: Contribution to journalReview article

    @article{d970b436373b42a3b24193d18bd32a38,
    title = "The Rickettsioses: A Practical Update",
    abstract = "Rickettsia are small, obligately intracellular, gram-negative bacilli. They are distributed among a variety of hematophagous arthropod vectors and cause illness throughout the world. Rickettsioses present as an acute undifferentiated febrile illness and are often accompanied by headache, myalgias, and malaise. Cutaneous manifestations include rash and eschar, which both occur at varying incidence depending on the infecting species. Serology is the mainstay of diagnosis, and the indirect immunofluorescence assay is the test of choice. Reactive antibodies are seldom present during early illness, so testing should be performed on both acute-phase and convalescent-phase sera. Doxycycline is the treatment of choice.",
    keywords = "Epidemic typhus, Murine typhus, Rickettsia prowazekii, Rickettsia rickettsii, Rickettsia typhi, Rocky mountain spotted fever, Spotted fever group rickettsioses, Vector-borne disease",
    author = "Lucas Blanton",
    year = "2019",
    month = "3",
    day = "1",
    doi = "10.1016/j.idc.2018.10.010",
    language = "English (US)",
    volume = "33",
    pages = "213--229",
    journal = "Infectious Disease Clinics of North America",
    issn = "0891-5520",
    publisher = "W.B. Saunders Ltd",
    number = "1",

    }

    TY - JOUR

    T1 - The Rickettsioses

    T2 - A Practical Update

    AU - Blanton, Lucas

    PY - 2019/3/1

    Y1 - 2019/3/1

    N2 - Rickettsia are small, obligately intracellular, gram-negative bacilli. They are distributed among a variety of hematophagous arthropod vectors and cause illness throughout the world. Rickettsioses present as an acute undifferentiated febrile illness and are often accompanied by headache, myalgias, and malaise. Cutaneous manifestations include rash and eschar, which both occur at varying incidence depending on the infecting species. Serology is the mainstay of diagnosis, and the indirect immunofluorescence assay is the test of choice. Reactive antibodies are seldom present during early illness, so testing should be performed on both acute-phase and convalescent-phase sera. Doxycycline is the treatment of choice.

    AB - Rickettsia are small, obligately intracellular, gram-negative bacilli. They are distributed among a variety of hematophagous arthropod vectors and cause illness throughout the world. Rickettsioses present as an acute undifferentiated febrile illness and are often accompanied by headache, myalgias, and malaise. Cutaneous manifestations include rash and eschar, which both occur at varying incidence depending on the infecting species. Serology is the mainstay of diagnosis, and the indirect immunofluorescence assay is the test of choice. Reactive antibodies are seldom present during early illness, so testing should be performed on both acute-phase and convalescent-phase sera. Doxycycline is the treatment of choice.

    KW - Epidemic typhus

    KW - Murine typhus

    KW - Rickettsia prowazekii

    KW - Rickettsia rickettsii

    KW - Rickettsia typhi

    KW - Rocky mountain spotted fever

    KW - Spotted fever group rickettsioses

    KW - Vector-borne disease

    UR - http://www.scopus.com/inward/record.url?scp=85060876004&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=85060876004&partnerID=8YFLogxK

    U2 - 10.1016/j.idc.2018.10.010

    DO - 10.1016/j.idc.2018.10.010

    M3 - Review article

    VL - 33

    SP - 213

    EP - 229

    JO - Infectious Disease Clinics of North America

    JF - Infectious Disease Clinics of North America

    SN - 0891-5520

    IS - 1

    ER -