The role of acute pancreatitis in pediatric burn patients

Haidy G. Rivero, Jong Lee, David Herndon, Gabriel A. Mecott, Gabriela A. Kulp, Robert Kraft, Natasha C. Brooks, Manuel Diblidox-Gonzales, Hal K. Hawkins, Marc G. Jeschke

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Few publications recognize acute pancreatitis as a complication after large burns, consequently the incidence and outcome acute pancreatitis after burn in children is not well defined. The aim of this study was to determine the incidence, morbidity, and mortality relating to acute pancreatitis in a pediatric burn population and to correlate clinical diagnosis with autopsy findings to determine the incidence of unrecognized pancreatitis. Records of 2699 patients with acute burns were reviewed. Acute pancreatitis was defined as abdominal pain and/or feeding intolerance in addition to a three-fold elevation of amylase and/or lipase. One-hundred twenty-seven burned children served as the control cohort. To assess the presence of autopsy confirmed AP in pediatric burn patients, we evaluated autopsy reports of 78 children who died from burns, looking for reported evidence of pancreatic inflammation, and fat/parenchymal necrosis. Our data show that acute pancreatitis in children has a low incidence after burn. The study included 2699 patients of which 13 were suffering acute pancreatitis (13/2699 = 0.05%). Mortality is significantly higher for the acute pancreatitis group vs. the control group, p < 0.05. Autopsy reports established 11 of 78 patients with evidence of pancreatitis, resulting in an incidence of 0.17% for pancreatitis at autopsy. Although it has low incidence, acute pancreatitis is associated with increased mortality in severely burned pediatric patients, which underlines the importance of increased vigilance in the evaluation and treatment of pancreatitis in burned children.

Original languageEnglish (US)
Pages (from-to)82-85
Number of pages4
JournalBurns
Volume37
Issue number1
DOIs
StatePublished - Feb 2011

Fingerprint

Pancreatitis
Pediatrics
Autopsy
Incidence
Burns
Mortality
Fat Necrosis
Amylases
Lipase
Abdominal Pain
Publications
Inflammation
Morbidity
Control Groups

Keywords

  • Burn
  • Pancreatitis
  • Pediatrics

ASJC Scopus subject areas

  • Emergency Medicine
  • Critical Care and Intensive Care Medicine
  • Surgery

Cite this

Rivero, H. G., Lee, J., Herndon, D., Mecott, G. A., Kulp, G. A., Kraft, R., ... Jeschke, M. G. (2011). The role of acute pancreatitis in pediatric burn patients. Burns, 37(1), 82-85. https://doi.org/10.1016/j.burns.2010.07.015

The role of acute pancreatitis in pediatric burn patients. / Rivero, Haidy G.; Lee, Jong; Herndon, David; Mecott, Gabriel A.; Kulp, Gabriela A.; Kraft, Robert; Brooks, Natasha C.; Diblidox-Gonzales, Manuel; Hawkins, Hal K.; Jeschke, Marc G.

In: Burns, Vol. 37, No. 1, 02.2011, p. 82-85.

Research output: Contribution to journalArticle

Rivero, HG, Lee, J, Herndon, D, Mecott, GA, Kulp, GA, Kraft, R, Brooks, NC, Diblidox-Gonzales, M, Hawkins, HK & Jeschke, MG 2011, 'The role of acute pancreatitis in pediatric burn patients', Burns, vol. 37, no. 1, pp. 82-85. https://doi.org/10.1016/j.burns.2010.07.015
Rivero HG, Lee J, Herndon D, Mecott GA, Kulp GA, Kraft R et al. The role of acute pancreatitis in pediatric burn patients. Burns. 2011 Feb;37(1):82-85. https://doi.org/10.1016/j.burns.2010.07.015
Rivero, Haidy G. ; Lee, Jong ; Herndon, David ; Mecott, Gabriel A. ; Kulp, Gabriela A. ; Kraft, Robert ; Brooks, Natasha C. ; Diblidox-Gonzales, Manuel ; Hawkins, Hal K. ; Jeschke, Marc G. / The role of acute pancreatitis in pediatric burn patients. In: Burns. 2011 ; Vol. 37, No. 1. pp. 82-85.
@article{f403dcaf0a9e4846b0c3c542df3e60d8,
title = "The role of acute pancreatitis in pediatric burn patients",
abstract = "Few publications recognize acute pancreatitis as a complication after large burns, consequently the incidence and outcome acute pancreatitis after burn in children is not well defined. The aim of this study was to determine the incidence, morbidity, and mortality relating to acute pancreatitis in a pediatric burn population and to correlate clinical diagnosis with autopsy findings to determine the incidence of unrecognized pancreatitis. Records of 2699 patients with acute burns were reviewed. Acute pancreatitis was defined as abdominal pain and/or feeding intolerance in addition to a three-fold elevation of amylase and/or lipase. One-hundred twenty-seven burned children served as the control cohort. To assess the presence of autopsy confirmed AP in pediatric burn patients, we evaluated autopsy reports of 78 children who died from burns, looking for reported evidence of pancreatic inflammation, and fat/parenchymal necrosis. Our data show that acute pancreatitis in children has a low incidence after burn. The study included 2699 patients of which 13 were suffering acute pancreatitis (13/2699 = 0.05{\%}). Mortality is significantly higher for the acute pancreatitis group vs. the control group, p < 0.05. Autopsy reports established 11 of 78 patients with evidence of pancreatitis, resulting in an incidence of 0.17{\%} for pancreatitis at autopsy. Although it has low incidence, acute pancreatitis is associated with increased mortality in severely burned pediatric patients, which underlines the importance of increased vigilance in the evaluation and treatment of pancreatitis in burned children.",
keywords = "Burn, Pancreatitis, Pediatrics",
author = "Rivero, {Haidy G.} and Jong Lee and David Herndon and Mecott, {Gabriel A.} and Kulp, {Gabriela A.} and Robert Kraft and Brooks, {Natasha C.} and Manuel Diblidox-Gonzales and Hawkins, {Hal K.} and Jeschke, {Marc G.}",
year = "2011",
month = "2",
doi = "10.1016/j.burns.2010.07.015",
language = "English (US)",
volume = "37",
pages = "82--85",
journal = "Burns",
issn = "0305-4179",
publisher = "Elsevier Limited",
number = "1",

}

TY - JOUR

T1 - The role of acute pancreatitis in pediatric burn patients

AU - Rivero, Haidy G.

AU - Lee, Jong

AU - Herndon, David

AU - Mecott, Gabriel A.

AU - Kulp, Gabriela A.

AU - Kraft, Robert

AU - Brooks, Natasha C.

AU - Diblidox-Gonzales, Manuel

AU - Hawkins, Hal K.

AU - Jeschke, Marc G.

PY - 2011/2

Y1 - 2011/2

N2 - Few publications recognize acute pancreatitis as a complication after large burns, consequently the incidence and outcome acute pancreatitis after burn in children is not well defined. The aim of this study was to determine the incidence, morbidity, and mortality relating to acute pancreatitis in a pediatric burn population and to correlate clinical diagnosis with autopsy findings to determine the incidence of unrecognized pancreatitis. Records of 2699 patients with acute burns were reviewed. Acute pancreatitis was defined as abdominal pain and/or feeding intolerance in addition to a three-fold elevation of amylase and/or lipase. One-hundred twenty-seven burned children served as the control cohort. To assess the presence of autopsy confirmed AP in pediatric burn patients, we evaluated autopsy reports of 78 children who died from burns, looking for reported evidence of pancreatic inflammation, and fat/parenchymal necrosis. Our data show that acute pancreatitis in children has a low incidence after burn. The study included 2699 patients of which 13 were suffering acute pancreatitis (13/2699 = 0.05%). Mortality is significantly higher for the acute pancreatitis group vs. the control group, p < 0.05. Autopsy reports established 11 of 78 patients with evidence of pancreatitis, resulting in an incidence of 0.17% for pancreatitis at autopsy. Although it has low incidence, acute pancreatitis is associated with increased mortality in severely burned pediatric patients, which underlines the importance of increased vigilance in the evaluation and treatment of pancreatitis in burned children.

AB - Few publications recognize acute pancreatitis as a complication after large burns, consequently the incidence and outcome acute pancreatitis after burn in children is not well defined. The aim of this study was to determine the incidence, morbidity, and mortality relating to acute pancreatitis in a pediatric burn population and to correlate clinical diagnosis with autopsy findings to determine the incidence of unrecognized pancreatitis. Records of 2699 patients with acute burns were reviewed. Acute pancreatitis was defined as abdominal pain and/or feeding intolerance in addition to a three-fold elevation of amylase and/or lipase. One-hundred twenty-seven burned children served as the control cohort. To assess the presence of autopsy confirmed AP in pediatric burn patients, we evaluated autopsy reports of 78 children who died from burns, looking for reported evidence of pancreatic inflammation, and fat/parenchymal necrosis. Our data show that acute pancreatitis in children has a low incidence after burn. The study included 2699 patients of which 13 were suffering acute pancreatitis (13/2699 = 0.05%). Mortality is significantly higher for the acute pancreatitis group vs. the control group, p < 0.05. Autopsy reports established 11 of 78 patients with evidence of pancreatitis, resulting in an incidence of 0.17% for pancreatitis at autopsy. Although it has low incidence, acute pancreatitis is associated with increased mortality in severely burned pediatric patients, which underlines the importance of increased vigilance in the evaluation and treatment of pancreatitis in burned children.

KW - Burn

KW - Pancreatitis

KW - Pediatrics

UR - http://www.scopus.com/inward/record.url?scp=78650518923&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78650518923&partnerID=8YFLogxK

U2 - 10.1016/j.burns.2010.07.015

DO - 10.1016/j.burns.2010.07.015

M3 - Article

C2 - 20851528

AN - SCOPUS:78650518923

VL - 37

SP - 82

EP - 85

JO - Burns

JF - Burns

SN - 0305-4179

IS - 1

ER -