The role of bacterial vaginosis and trichomonas in HIV transmission across the female genital tract

Paria Mirmonsef; Laurie Krass; Alan Landay; Gregory T. Spear

doi:10.2174/157016212800618165

The role of bacterial vaginosis and trichomonas in HIV transmission across the female genital tract

Paria Mirmonsef, Laurie Krass, Alan Landay, Gregory T. Spear

Research output: Contribution to journal › Article › peer-review

82 Scopus citations

Abstract

Bacterial vaginosis (BV) and Trichomonas vaginalis (TV) infections are both very common and are associated with increased risk of sexual transmission of HIV. There are several mechanisms by which BV and TV could affect susceptibility including inducing pro-inflammatory cytokines and disrupting mucosal barrier function. This review highlights recent advances in our understanding of how these genital conditions lead to an increased risk of HIV infection in women.

Original language	English (US)
Pages (from-to)	202-210
Number of pages	9
Journal	Current HIV Research
Volume	10
Issue number	3
DOIs	https://doi.org/10.2174/157016212800618165
State	Published - Apr 2012
Externally published	Yes

Keywords

Bacterial vaginosis
HIV
Inflammation
Trichomonas vaginalis

ASJC Scopus subject areas

Infectious Diseases
Virology

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10.2174/157016212800618165

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abstract = "Bacterial vaginosis (BV) and Trichomonas vaginalis (TV) infections are both very common and are associated with increased risk of sexual transmission of HIV. There are several mechanisms by which BV and TV could affect susceptibility including inducing pro-inflammatory cytokines and disrupting mucosal barrier function. This review highlights recent advances in our understanding of how these genital conditions lead to an increased risk of HIV infection in women.",

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AU - Spear, Gregory T.

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AB - Bacterial vaginosis (BV) and Trichomonas vaginalis (TV) infections are both very common and are associated with increased risk of sexual transmission of HIV. There are several mechanisms by which BV and TV could affect susceptibility including inducing pro-inflammatory cytokines and disrupting mucosal barrier function. This review highlights recent advances in our understanding of how these genital conditions lead to an increased risk of HIV infection in women.

KW - Bacterial vaginosis

KW - HIV

KW - Inflammation

KW - Trichomonas vaginalis

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The role of bacterial vaginosis and trichomonas in HIV transmission across the female genital tract

Abstract

Keywords

ASJC Scopus subject areas

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