Abstract
The majority of patients with pancreatic cancer present with disease that is unresectable due to local invasion. This article reviews the evidence (or lack thereof) that chemoradiation therapy (CRT) helps these patients in four areas: survival, tumor downstaging, palliation of obstructive symptoms, and pain control. We believe that CRT allows a small percentage of patients with locally advanced disease to undergo potentially curative resection while providing effective palliative treatment.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 109-113 |
| Number of pages | 5 |
| Journal | HPB |
| Volume | 7 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2005 |
| Externally published | Yes |
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Keywords
- Chemoradiation
- Neoadjuvant
- Palliation
- Pancreatic cancer
- Pancreaticoduodenectomy
ASJC Scopus subject areas
- Gastroenterology
Cite this
The role of chemoradiation therapy in locally advanced pancreatic cancer. / White, Rebekah R.; Reddy, Srinivas; Tyler, Douglas.
In: HPB, Vol. 7, No. 2, 2005, p. 109-113.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The role of chemoradiation therapy in locally advanced pancreatic cancer
AU - White, Rebekah R.
AU - Reddy, Srinivas
AU - Tyler, Douglas
PY - 2005
Y1 - 2005
N2 - The majority of patients with pancreatic cancer present with disease that is unresectable due to local invasion. This article reviews the evidence (or lack thereof) that chemoradiation therapy (CRT) helps these patients in four areas: survival, tumor downstaging, palliation of obstructive symptoms, and pain control. We believe that CRT allows a small percentage of patients with locally advanced disease to undergo potentially curative resection while providing effective palliative treatment.
AB - The majority of patients with pancreatic cancer present with disease that is unresectable due to local invasion. This article reviews the evidence (or lack thereof) that chemoradiation therapy (CRT) helps these patients in four areas: survival, tumor downstaging, palliation of obstructive symptoms, and pain control. We believe that CRT allows a small percentage of patients with locally advanced disease to undergo potentially curative resection while providing effective palliative treatment.
KW - Chemoradiation
KW - Neoadjuvant
KW - Palliation
KW - Pancreatic cancer
KW - Pancreaticoduodenectomy
UR - http://www.scopus.com/inward/record.url?scp=20044368460&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=20044368460&partnerID=8YFLogxK
U2 - 10.1080/13651820510028963
DO - 10.1080/13651820510028963
M3 - Article
C2 - 18333172
AN - SCOPUS:20044368460
VL - 7
SP - 109
EP - 113
JO - HPB
JF - HPB
SN - 1365-182X
IS - 2
ER -