The role of chemoradiation therapy in locally advanced pancreatic cancer

Rebekah R. White, Srinivas Reddy, Douglas S. Tyler

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


The majority of patients with pancreatic cancer present with disease that is unresectable due to local invasion. This article reviews the evidence (or lack thereof) that chemoradiation therapy (CRT) helps these patients in four areas: survival, tumor downstaging, palliation of obstructive symptoms, and pain control. We believe that CRT allows a small percentage of patients with locally advanced disease to undergo potentially curative resection while providing effective palliative treatment.

Original languageEnglish (US)
Pages (from-to)109-113
Number of pages5
Issue number2
StatePublished - 2005
Externally publishedYes


  • Chemoradiation
  • Neoadjuvant
  • Palliation
  • Pancreatic cancer
  • Pancreaticoduodenectomy

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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