The role of dynamic changes in blood perfusion and optical properties in thermal coagulation of the prostate

Beop Min Kim, Steven L. Jacques, Sohi Rastegar, Sharon Thomsen, Massoud Motamedi

    Research output: Contribution to journalConference articlepeer-review

    17 Scopus citations

    Abstract

    The dynamic evolution of the coagulation front in laser irradiated prostate tissue is simulated using a nonlinear finite element method (NFEM) which takes into account the temperature and thermal damage dependence of blood perfusion rate and optical properties. Using this nonlinear model, it wasfound that the hyperemic ringformed at the periphery of the coagulationfront reduces heatpenetration significantly and the increased scattering near the tissue surface reduces the light energy deposition in the deep region. Thefinal damage depth would be overestimated by about 50% ifthe effect oftemperature and damage dependence of blood perfusion and opticalproperties modeling is disregarded.

    Original languageEnglish (US)
    Pages (from-to)443-450
    Number of pages8
    JournalProceedings of SPIE - The International Society for Optical Engineering
    Volume2391
    DOIs
    StatePublished - May 22 1995
    EventLaser-Tissue Interaction VI 1995 - San Jose, United States
    Duration: Feb 1 1995Feb 8 1995

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Condensed Matter Physics
    • Computer Science Applications
    • Applied Mathematics
    • Electrical and Electronic Engineering

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