The role of massive transfusion protocols in obstetrics

Luis D. Pacheco, George R. Saade, Maged M. Costantine, Steven L. Clark, Gary D.V. Hankins

Research output: Contribution to journalReview articlepeer-review

33 Scopus citations


Obstetric hemorrhage is a leading cause of maternal mortality worldwide. New concepts involving the pathophysiology of hemorrhage have been described and include early activation of both the protein C and fibrinolytic pathways. New tendencies in hemorrhage treatment include the use of hemostatic resuscitation. Massive transfusion protocols involve the early utilization of blood products and limit the traditional approach of early massive crystalloid based resuscitation. The evidence behind hemostatic resuscitation is still limited.

Original languageEnglish (US)
Pages (from-to)1-4
Number of pages4
JournalAmerican Journal of Perinatology
Issue number1
StatePublished - 2013


  • hemostasis
  • massive transfusion
  • obstetric hemorrhage

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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