The role of mites in the transmission and maintenance of Hantaan virus (Hantavirus

Bunyaviridae)

Xue jie Yu

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

This review examines the evidence indicating a role for parasitic mites in the transmission and maintenance of Hantaan virus in nature. The available data, much of it from recent studies in China, indicate that both trombiculid and gamasid mites are naturally infected with Hantaan virus and that infected mites can transmit the virus by bite to laboratory mice and transovarially (vertically) through eggs to their offspring. Collectively, these findings challenge the current paradigm of hantavirus transmission, namely, that rodents serve as the reservoir of human pathogenic hantaviruses in nature and that humans are infected with these viruses by inhalation of aerosols of infectious rodent excreta. Further research is needed to confirm the mite-hantavirus association and to determine if parasitic mites are in fact the major source and principal vectors of human pathogenic hantaviruses, such as Hantaan. If the mite hypothesis is correct, then it will significantly alter current concepts about the epidemiology, prevention, and control of human hantavirus infection.

Original languageEnglish (US)
Pages (from-to)1693-1699
Number of pages7
JournalThe Journal of infectious diseases
Volume210
Issue number11
DOIs
StatePublished - Dec 1 2014

Fingerprint

Hantaan virus
Bunyaviridae
Hantavirus
Mites
Maintenance
Rodentia
Hantavirus Infections
Trombiculidae
Viruses
Bites and Stings
Aerosols
Inhalation
Eggs
China
Epidemiology
Research

Keywords

  • arbovirus infection
  • Hantaan virus
  • hantavirus infection
  • hantavirus transmission
  • hemorrhagic fever with renal syndrome
  • mite-borne disease
  • vector biology

ASJC Scopus subject areas

  • Medicine(all)

Cite this

The role of mites in the transmission and maintenance of Hantaan virus (Hantavirus : Bunyaviridae). / Yu, Xue jie.

In: The Journal of infectious diseases, Vol. 210, No. 11, 01.12.2014, p. 1693-1699.

Research output: Contribution to journalArticle

@article{506a1fab0cf84cb79b387985d55e1964,
title = "The role of mites in the transmission and maintenance of Hantaan virus (Hantavirus: Bunyaviridae)",
abstract = "This review examines the evidence indicating a role for parasitic mites in the transmission and maintenance of Hantaan virus in nature. The available data, much of it from recent studies in China, indicate that both trombiculid and gamasid mites are naturally infected with Hantaan virus and that infected mites can transmit the virus by bite to laboratory mice and transovarially (vertically) through eggs to their offspring. Collectively, these findings challenge the current paradigm of hantavirus transmission, namely, that rodents serve as the reservoir of human pathogenic hantaviruses in nature and that humans are infected with these viruses by inhalation of aerosols of infectious rodent excreta. Further research is needed to confirm the mite-hantavirus association and to determine if parasitic mites are in fact the major source and principal vectors of human pathogenic hantaviruses, such as Hantaan. If the mite hypothesis is correct, then it will significantly alter current concepts about the epidemiology, prevention, and control of human hantavirus infection.",
keywords = "arbovirus infection, Hantaan virus, hantavirus infection, hantavirus transmission, hemorrhagic fever with renal syndrome, mite-borne disease, vector biology",
author = "Yu, {Xue jie}",
year = "2014",
month = "12",
day = "1",
doi = "10.1093/infdis/jiu336",
language = "English (US)",
volume = "210",
pages = "1693--1699",
journal = "Journal of Infectious Diseases",
issn = "0022-1899",
publisher = "Oxford University Press",
number = "11",

}

TY - JOUR

T1 - The role of mites in the transmission and maintenance of Hantaan virus (Hantavirus

T2 - Bunyaviridae)

AU - Yu, Xue jie

PY - 2014/12/1

Y1 - 2014/12/1

N2 - This review examines the evidence indicating a role for parasitic mites in the transmission and maintenance of Hantaan virus in nature. The available data, much of it from recent studies in China, indicate that both trombiculid and gamasid mites are naturally infected with Hantaan virus and that infected mites can transmit the virus by bite to laboratory mice and transovarially (vertically) through eggs to their offspring. Collectively, these findings challenge the current paradigm of hantavirus transmission, namely, that rodents serve as the reservoir of human pathogenic hantaviruses in nature and that humans are infected with these viruses by inhalation of aerosols of infectious rodent excreta. Further research is needed to confirm the mite-hantavirus association and to determine if parasitic mites are in fact the major source and principal vectors of human pathogenic hantaviruses, such as Hantaan. If the mite hypothesis is correct, then it will significantly alter current concepts about the epidemiology, prevention, and control of human hantavirus infection.

AB - This review examines the evidence indicating a role for parasitic mites in the transmission and maintenance of Hantaan virus in nature. The available data, much of it from recent studies in China, indicate that both trombiculid and gamasid mites are naturally infected with Hantaan virus and that infected mites can transmit the virus by bite to laboratory mice and transovarially (vertically) through eggs to their offspring. Collectively, these findings challenge the current paradigm of hantavirus transmission, namely, that rodents serve as the reservoir of human pathogenic hantaviruses in nature and that humans are infected with these viruses by inhalation of aerosols of infectious rodent excreta. Further research is needed to confirm the mite-hantavirus association and to determine if parasitic mites are in fact the major source and principal vectors of human pathogenic hantaviruses, such as Hantaan. If the mite hypothesis is correct, then it will significantly alter current concepts about the epidemiology, prevention, and control of human hantavirus infection.

KW - arbovirus infection

KW - Hantaan virus

KW - hantavirus infection

KW - hantavirus transmission

KW - hemorrhagic fever with renal syndrome

KW - mite-borne disease

KW - vector biology

UR - http://www.scopus.com/inward/record.url?scp=84922287244&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84922287244&partnerID=8YFLogxK

U2 - 10.1093/infdis/jiu336

DO - 10.1093/infdis/jiu336

M3 - Article

VL - 210

SP - 1693

EP - 1699

JO - Journal of Infectious Diseases

JF - Journal of Infectious Diseases

SN - 0022-1899

IS - 11

ER -