The Role of Monoclonal Antibodies in the Treatment of Atherosclerosis

Jimmy Hong; Leonardo Salazar; Joanne Acevedo; Ravi Thakker; Hani Jneid; Mostafa Shalaby; Jennifer McCracken; Wissam Khalife

doi:10.1016/j.cpcardiol.2023.101585

The Role of Monoclonal Antibodies in the Treatment of Atherosclerosis

Jimmy Hong, Leonardo Salazar, Joanne Acevedo, Ravi Thakker, Hani Jneid, Mostafa Shalaby, Jennifer McCracken, Wissam Khalife

Internal Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

Atherosclerosis is an inflammatory disease that involves antibody immune responses. Progression of hyperlipidemia can lead to atherosclerosis and subsequently cardiovascular diseases with high mortality. Additional lipid-lowering therapies other than statins are currently being studied, such as monoclonal antibodies. In this contemporary review, we examine the various monoclonal antibody therapies targeted toward atherosclerotic disease.

Original language	English (US)
Article number	101585
Journal	Current Problems in Cardiology
Volume	48
Issue number	4
DOIs	https://doi.org/10.1016/j.cpcardiol.2023.101585
State	Published - Apr 2023

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.cpcardiol.2023.101585

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title = "The Role of Monoclonal Antibodies in the Treatment of Atherosclerosis",

abstract = "Atherosclerosis is an inflammatory disease that involves antibody immune responses. Progression of hyperlipidemia can lead to atherosclerosis and subsequently cardiovascular diseases with high mortality. Additional lipid-lowering therapies other than statins are currently being studied, such as monoclonal antibodies. In this contemporary review, we examine the various monoclonal antibody therapies targeted toward atherosclerotic disease.",

author = "Jimmy Hong and Leonardo Salazar and Joanne Acevedo and Ravi Thakker and Hani Jneid and Mostafa Shalaby and Jennifer McCracken and Wissam Khalife",

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AU - Hong, Jimmy

AU - Salazar, Leonardo

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AU - Jneid, Hani

AU - Shalaby, Mostafa

AU - McCracken, Jennifer

AU - Khalife, Wissam

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AB - Atherosclerosis is an inflammatory disease that involves antibody immune responses. Progression of hyperlipidemia can lead to atherosclerosis and subsequently cardiovascular diseases with high mortality. Additional lipid-lowering therapies other than statins are currently being studied, such as monoclonal antibodies. In this contemporary review, we examine the various monoclonal antibody therapies targeted toward atherosclerotic disease.

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The Role of Monoclonal Antibodies in the Treatment of Atherosclerosis

Abstract

ASJC Scopus subject areas

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