DIE ROLLE DES PLASMACOLLOIDOSMOTISCHEN DRUCKES IM HAMORRHAGISCHEN SCHOCK UND BEI DER PULMONALEN UND SYSTEMISCHEN ODEMBILDUNG

Translated title of the contribution: The role of the plasma colloid osmotic pressure in hemorrhagic shock and in pulmonary and systemic edema formation

M. L. Nerlich, George Kramer, J. A. Sturm

Research output: Contribution to journalArticle

Abstract

The effects of reduced colloid osmotic pressure (COP), as seen after resuscitation from hemorrhagic shock, on fluid filtration and water content in the pulmonary and systemic microcirculation were examined during acute plasmapheresis in seven nonanesthetized sheep prepared with chronic lung and systemic lymph fistulas. A 50.5% reduction of COP resulted in significant increases in lymph flow (pulmonary 311% of baseline, systemic 196%) and a significant increase in soft tissue water content, but there was no change in extravascular pulmonary water. The lung seems to be prevented by lymphatic safety factors against development of hypoproteinemic edema in moderate COP reductions. Pulmonary edema after hemorrhagic shock cannot be explained by reduced COP.

Original languageGerman
Pages (from-to)201-205
Number of pages5
JournalLangenbecks Archiv fur Chirurgie
Volume359
Issue numberSuppl.
StatePublished - 1983
Externally publishedYes

Fingerprint

Hemorrhagic Shock
Osmotic Pressure
Colloids
Pulmonary Edema
Lung
Lymph
Water
Plasmapheresis
Microcirculation
Resuscitation
Fistula
Edema
Sheep
Safety

ASJC Scopus subject areas

  • Surgery

Cite this

DIE ROLLE DES PLASMACOLLOIDOSMOTISCHEN DRUCKES IM HAMORRHAGISCHEN SCHOCK UND BEI DER PULMONALEN UND SYSTEMISCHEN ODEMBILDUNG. / Nerlich, M. L.; Kramer, George; Sturm, J. A.

In: Langenbecks Archiv fur Chirurgie, Vol. 359, No. Suppl., 1983, p. 201-205.

Research output: Contribution to journalArticle

@article{b8c866d908854626951bb7999f591a8a,
title = "DIE ROLLE DES PLASMACOLLOIDOSMOTISCHEN DRUCKES IM HAMORRHAGISCHEN SCHOCK UND BEI DER PULMONALEN UND SYSTEMISCHEN ODEMBILDUNG",
abstract = "The effects of reduced colloid osmotic pressure (COP), as seen after resuscitation from hemorrhagic shock, on fluid filtration and water content in the pulmonary and systemic microcirculation were examined during acute plasmapheresis in seven nonanesthetized sheep prepared with chronic lung and systemic lymph fistulas. A 50.5{\%} reduction of COP resulted in significant increases in lymph flow (pulmonary 311{\%} of baseline, systemic 196{\%}) and a significant increase in soft tissue water content, but there was no change in extravascular pulmonary water. The lung seems to be prevented by lymphatic safety factors against development of hypoproteinemic edema in moderate COP reductions. Pulmonary edema after hemorrhagic shock cannot be explained by reduced COP.",
author = "Nerlich, {M. L.} and George Kramer and Sturm, {J. A.}",
year = "1983",
language = "German",
volume = "359",
pages = "201--205",
journal = "Langenbeck's Archives of Surgery",
issn = "1435-2443",
publisher = "Springer Verlag",
number = "Suppl.",

}

TY - JOUR

T1 - DIE ROLLE DES PLASMACOLLOIDOSMOTISCHEN DRUCKES IM HAMORRHAGISCHEN SCHOCK UND BEI DER PULMONALEN UND SYSTEMISCHEN ODEMBILDUNG

AU - Nerlich, M. L.

AU - Kramer, George

AU - Sturm, J. A.

PY - 1983

Y1 - 1983

N2 - The effects of reduced colloid osmotic pressure (COP), as seen after resuscitation from hemorrhagic shock, on fluid filtration and water content in the pulmonary and systemic microcirculation were examined during acute plasmapheresis in seven nonanesthetized sheep prepared with chronic lung and systemic lymph fistulas. A 50.5% reduction of COP resulted in significant increases in lymph flow (pulmonary 311% of baseline, systemic 196%) and a significant increase in soft tissue water content, but there was no change in extravascular pulmonary water. The lung seems to be prevented by lymphatic safety factors against development of hypoproteinemic edema in moderate COP reductions. Pulmonary edema after hemorrhagic shock cannot be explained by reduced COP.

AB - The effects of reduced colloid osmotic pressure (COP), as seen after resuscitation from hemorrhagic shock, on fluid filtration and water content in the pulmonary and systemic microcirculation were examined during acute plasmapheresis in seven nonanesthetized sheep prepared with chronic lung and systemic lymph fistulas. A 50.5% reduction of COP resulted in significant increases in lymph flow (pulmonary 311% of baseline, systemic 196%) and a significant increase in soft tissue water content, but there was no change in extravascular pulmonary water. The lung seems to be prevented by lymphatic safety factors against development of hypoproteinemic edema in moderate COP reductions. Pulmonary edema after hemorrhagic shock cannot be explained by reduced COP.

UR - http://www.scopus.com/inward/record.url?scp=0020961730&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020961730&partnerID=8YFLogxK

M3 - Article

VL - 359

SP - 201

EP - 205

JO - Langenbeck's Archives of Surgery

JF - Langenbeck's Archives of Surgery

SN - 1435-2443

IS - Suppl.

ER -