The Saccharomyces cerevisiae DNA Repair Gene RAD2 Is Regulated in Meiosis but Not during the Mitotic Cell Cycle

Kiran Madura, Satya Prakash

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The expression of the RAD2 gene of Saccharomyces cerevisiae is elevated upon DNA damage. Here, we show that KAD2 transcript levels also rise approximately eightfold during meiosis but remain constant during the mitotic cell cycle. The period of maximal RAD2 mRNA accumulation during meiosis is consistent with a possible role of KAD2 in a late stage of recombination, in mismatch repair of heteroduplexes, or both.

Original languageEnglish (US)
Pages (from-to)3256-3257
Number of pages2
JournalMolecular and Cellular Biology
Volume10
Issue number6
StatePublished - Jun 1990
Externally publishedYes

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Meiosis
DNA Repair
Saccharomyces cerevisiae
Cell Cycle
DNA Mismatch Repair
Genetic Recombination
Genes
DNA Damage
Gene Expression
Messenger RNA

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cell Biology

Cite this

The Saccharomyces cerevisiae DNA Repair Gene RAD2 Is Regulated in Meiosis but Not during the Mitotic Cell Cycle. / Madura, Kiran; Prakash, Satya.

In: Molecular and Cellular Biology, Vol. 10, No. 6, 06.1990, p. 3256-3257.

Research output: Contribution to journalArticle

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