The surgical management of abdominal pain in the multiple myeloma patient

Jared Garrett, Vicki Klimberg, Elias Anaissie, Bart Barlogie, Richard Turnage, Brian D. Badgwell

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Background: The purpose of this retrospective study was to characterize the presentation, treatment, and outcomes of patients with multiple myeloma requiring surgical evaluation for abdominal pain. Methods: Medical records of patients with myeloma and abdominal pain evaluated by surgery over a period of 18 months were examined. Results: Twenty-one patients underwent surgical evaluation, with 23 diagnoses. Neutropenic enterocolitis (n = 5 [22%]) and ileus (n = 4 [17%]) were common diagnoses. Eleven patients (52%) were neutropenic. Peritonitis was noted in only 1 patient. Eastern Cooperative Oncology Group performance status was either 3 or 4 in most patients (67%). Surgery was performed in 5 patients. The 90-day mortality rate for all patients was 43%, with all deaths secondary to sepsis in patients managed without surgery. Conclusions: Patients with myeloma requiring surgical evaluation for abdominal pain have a unique differential diagnosis, with notable findings at presentation including the presence of cytopenia, lack of peritoneal signs, and low performance status.

Original languageEnglish (US)
Pages (from-to)127-131
Number of pages5
JournalAmerican Journal of Surgery
Volume203
Issue number2
DOIs
StatePublished - Feb 2012
Externally publishedYes

Keywords

  • Abdominal pain
  • Multiple myeloma
  • Surgery

ASJC Scopus subject areas

  • Surgery

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