TY - JOUR
T1 - The Surgical Management of Nerve Gaps
T2 - Present and Future
AU - Bassilios Habre, Samer
AU - Bond, Grant
AU - Jing, Xi Lin
AU - Kostopoulos, Epameinondas
AU - Wallace, Robert D.
AU - Konofaos, Petros
N1 - Publisher Copyright:
Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2018/3/1
Y1 - 2018/3/1
N2 - Peripheral nerve injuries can result in significant morbidity, including motor and/or sensory loss, which can affect significantly the life of the patient. Nowadays, the gold standard for the treatment of nerve section is end-to-end neurorrhaphy. Unfortunately, in some cases, there is segmental loss of the nerve trunk. Nerve mobilization allows primary repair of the sectioned nerve by end-to-end neurorrhaphy if the gap is less than 1 cm. When the nerve gap exceeds 1 cm, autologous nerve grafting is the gold standard of treatment. To overcome the limited availability and the donor site morbidity, other techniques have been used: vascularized nerve grafts, cellular and acellular allografts, nerve conduits, nerve transfers, and end-to-side neurorrhaphy. The purpose of this review is to present an overview of the literature on the applications of these techniques in peripheral nerve repair. Furthermore, preoperative evaluation, timing of repair, and future perspectives are also discussed.
AB - Peripheral nerve injuries can result in significant morbidity, including motor and/or sensory loss, which can affect significantly the life of the patient. Nowadays, the gold standard for the treatment of nerve section is end-to-end neurorrhaphy. Unfortunately, in some cases, there is segmental loss of the nerve trunk. Nerve mobilization allows primary repair of the sectioned nerve by end-to-end neurorrhaphy if the gap is less than 1 cm. When the nerve gap exceeds 1 cm, autologous nerve grafting is the gold standard of treatment. To overcome the limited availability and the donor site morbidity, other techniques have been used: vascularized nerve grafts, cellular and acellular allografts, nerve conduits, nerve transfers, and end-to-side neurorrhaphy. The purpose of this review is to present an overview of the literature on the applications of these techniques in peripheral nerve repair. Furthermore, preoperative evaluation, timing of repair, and future perspectives are also discussed.
KW - allograft
KW - autograft
KW - electromyography
KW - nerve regeneration
KW - peripheral nerve injury
UR - http://www.scopus.com/inward/record.url?scp=85042359362&partnerID=8YFLogxK
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U2 - 10.1097/SAP.0000000000001252
DO - 10.1097/SAP.0000000000001252
M3 - Article
C2 - 29166306
AN - SCOPUS:85042359362
SN - 0148-7043
VL - 80
SP - 252
EP - 261
JO - Annals of plastic surgery
JF - Annals of plastic surgery
IS - 3
ER -