The synthesis of chiral 1,2,4-benzothiadiazine derivatives

Nadiia V. Briukhovetska, Nataliya P. Kolesnyk, Alexander M. Chernega, Sergii Buth, Yuriy G. Shermolovich

Research output: Contribution to journalArticle


Novel enantiomerically pure benzothiadiazines were prepared using the commercially available enantiopure (1R,2S,5R)-(-)-menthol and 1,7-dichloro-3-trifluoromethyl-1λ4-benzo[1,2,4]thiadia zine.

Original languageEnglish (US)
Pages (from-to)271-275
Number of pages5
JournalTetrahedron Asymmetry
Issue number2
StatePublished - Feb 14 2007
Externally publishedYes


ASJC Scopus subject areas

  • Inorganic Chemistry
  • Organic Chemistry
  • Materials Chemistry
  • Drug Discovery

Cite this

Briukhovetska, N. V., Kolesnyk, N. P., Chernega, A. M., Buth, S., & Shermolovich, Y. G. (2007). The synthesis of chiral 1,2,4-benzothiadiazine derivatives. Tetrahedron Asymmetry, 18(2), 271-275.