The use of mirtazapine in difficult-to-treat patient populations

Robert M A Hirschfeld

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Patients who have failed previous antidepressant treatment present substantial clinical management challenges. Similarly, elderly patients require special attention. Three recent studies have shown that mirtazapine has a role to play in the management of these patients. Mirtazapine has proved effective in the treatment of patients who were resistant or intolerant to selective serotonin reuptake inhibitors (SSRIs) and the switch to mirtazapine could be made immediately without the necessity for a taper period. In a double-blind study in patients who were resistant to SSRI treatment, mirtazapine had a more rapid onset of action than sertraline. Mirtazapine has also proved effective in elderly depressed patients and again showed a faster onset of action than another of the SSRIs, paroxetine.

Original languageEnglish (US)
JournalHuman Psychopharmacology
Volume17
Issue numberSUPPL. 1
DOIs
StatePublished - 2002

Fingerprint

Serotonin Uptake Inhibitors
Population
Sertraline
Paroxetine
Double-Blind Method
Antidepressive Agents
mirtazapine
Therapeutics

Keywords

  • Depression
  • Elderly
  • Mirtazapine
  • Onset of action
  • SSRI failure

ASJC Scopus subject areas

  • Pharmacology
  • Psychology(all)
  • Neuroscience(all)
  • Pharmacology (medical)
  • Psychiatry and Mental health
  • Neurology
  • Clinical Neurology

Cite this

The use of mirtazapine in difficult-to-treat patient populations. / Hirschfeld, Robert M A.

In: Human Psychopharmacology, Vol. 17, No. SUPPL. 1, 2002.

Research output: Contribution to journalArticle

Hirschfeld, Robert M A. / The use of mirtazapine in difficult-to-treat patient populations. In: Human Psychopharmacology. 2002 ; Vol. 17, No. SUPPL. 1.
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