The VE-cadherin binding domain of fibrinogen induces endothelial barrier permeability and enhances transendothelial migration of malignant breast epithelial cells

Keyphrases

• Ligand-binding Domain 100%
• Transendothelial Migration 100%
• Breast Epithelial Cells 100%
• Fibrinogen 100%
• Endothelial Permeability 100%
• Vascular Endothelial Cadherin (VE-cadherin) 100%
• Cadherin Binding 100%
• Binding Interaction 11%
• Breast Cancer Cells 11%
• Metastatic Breast Cancer 11%
• MDA-MB-231 11%
• Molecular Mechanism 5%
• Inflammation 5%
• Cardiovascular Disease 5%
• Fibrin Deposition 5%
• Molecular Targets 5%
• Culture System 5%
• Epithelial Barrier 5%
• Molecular Switches 5%
• Angiogenesis 5%
• Nonmalignant 5%
• Lymph Node Metastasis 5%
• Neoplasia 5%
• Synthetic Peptides 5%
• Estrogen Receptor Status 5%
• E-cadherin 5%
• MCF10A 5%
• MCF10A Cells 5%
• Endothelial Cell Proliferation 5%
• MCF-7 5%
• Endothelial Adhesion Molecules 5%
• Highly Aggressive 5%
• Human Umbilical Vein 5%
• Exudation 5%
• Transwell Insert 5%
• Plasma Fibrinogen 5%
• Missing Residues 5%
• Leukocyte Diapedesis 5%
• Tumor Emboli 5%
• Breast Cancer Phenotype 5%
• Blood-borne Metastasis 5%
• Cadherin-like Receptor 5%
• Dose-dependent 5%
• Therapeutic Interventions 5%

Immunology and Microbiology

• VE-cadherin 100%
• Permeability Barrier 100%
• Fibrinogen 100%
• Cancer Cell 12%
• Endothelial Cells 12%
• Blood Plasma 6%
• Cell Proliferation 6%
• Leukocyte 6%
• Angiogenesis 6%
• Cadherin 6%
• Fibrin Deposition 6%
• Diapedesis 6%
• Umbilical Vein 6%
• Fibrinogen Blood Level 6%
• Cell Adhesion Proteins 6%
• Cardiovascular System 6%
• Peptides 6%
• Inflammation 6%
• Fibrin 6%