Thermally induced birefringence changes in cartilage using polarization sensitive optical coherence tomography

J. I. Youn, Gracie Vargas, M. G. Ducros, S. A. Telenkov, B. J F Wong, T. E. Milner

Research output: Chapter in Book/Report/Conference proceedingConference contribution

10 Citations (Scopus)

Abstract

Thermodynamic induced changes in birefringence of nasal septal cartilage following Nd:YAG laser irradiation were investigated using a polarization-sensitive optical coherence tomography (PSOCT) system. Birefringence in cartilage is due to the asymmetrical collagen fibril structure and may change if the underlying structure is disrupted due to local heat generation by absorption of laser radiation. A PSOCT instrument and an infrared imaging radiometer were used to record, respectively, depth-resolved images of the Stokes parameters of light backscattered from ex vivo porcine nasal septal cartilage and radiometric temperature changes following laser irradiation. PSOCT images of cartilage were recorded before (control), during, and after laser irradiation. From the measured Stokes parameters (I, Q, U, and V), an estimate of the relative phase retardation between two orthogonal polarizations was computed to determine birefringence in cartilage. Stokes parameter images of light backscattered from cartilage show significant changes due to laser irradiation. From our experiments we differentiate dehydration and thermal denaturation effects and observe the birefringence changes only in the dehydration effect. Therefore, a dynamic measurement of birefringence changes in cartilage using PSOCT as a feedback control methodology to monitor thermal denaturation is problematic in non-ablative surgical procedures such as laser assisted cartilage reshaping.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsD.D. Duncan, S.L. Jacques, P.C. Johnson
Pages213-220
Number of pages8
Volume4257
DOIs
StatePublished - 2001
Externally publishedYes
EventLaser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical - San Jose, CA, United States
Duration: Jan 21 2001Jan 24 2001

Other

OtherLaser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical
CountryUnited States
CitySan Jose, CA
Period1/21/011/24/01

Fingerprint

cartilage
Optical tomography
Cartilage
Birefringence
birefringence
tomography
Polarization
Laser beam effects
polarization
Denaturation
irradiation
biopolymer denaturation
Dehydration
dehydration
lasers
heat generation
Heat generation
Infrared imaging
Radiometers
collagens

Keywords

  • Birefringence
  • Cartilage
  • Polarization Sensitive Optical Coherence Tomography
  • Stokes Parameters

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Youn, J. I., Vargas, G., Ducros, M. G., Telenkov, S. A., Wong, B. J. F., & Milner, T. E. (2001). Thermally induced birefringence changes in cartilage using polarization sensitive optical coherence tomography. In D. D. Duncan, S. L. Jacques, & P. C. Johnson (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4257, pp. 213-220) https://doi.org/10.1117/12.434742

Thermally induced birefringence changes in cartilage using polarization sensitive optical coherence tomography. / Youn, J. I.; Vargas, Gracie; Ducros, M. G.; Telenkov, S. A.; Wong, B. J F; Milner, T. E.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / D.D. Duncan; S.L. Jacques; P.C. Johnson. Vol. 4257 2001. p. 213-220.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Youn, JI, Vargas, G, Ducros, MG, Telenkov, SA, Wong, BJF & Milner, TE 2001, Thermally induced birefringence changes in cartilage using polarization sensitive optical coherence tomography. in DD Duncan, SL Jacques & PC Johnson (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 4257, pp. 213-220, Laser-Tissue Interaction XII: Photochemical, Photothermal, and Photomechanical, San Jose, CA, United States, 1/21/01. https://doi.org/10.1117/12.434742
Youn JI, Vargas G, Ducros MG, Telenkov SA, Wong BJF, Milner TE. Thermally induced birefringence changes in cartilage using polarization sensitive optical coherence tomography. In Duncan DD, Jacques SL, Johnson PC, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4257. 2001. p. 213-220 https://doi.org/10.1117/12.434742
Youn, J. I. ; Vargas, Gracie ; Ducros, M. G. ; Telenkov, S. A. ; Wong, B. J F ; Milner, T. E. / Thermally induced birefringence changes in cartilage using polarization sensitive optical coherence tomography. Proceedings of SPIE - The International Society for Optical Engineering. editor / D.D. Duncan ; S.L. Jacques ; P.C. Johnson. Vol. 4257 2001. pp. 213-220
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