Thermally-induced changes in mechanical properties of tissue during CW laser ablation

Gerald L. LeCarpentier, Massoud Motamedi, A. J. Welch

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Thermal alterations of tissue as they relate to the initiation of continuous wave (cw) laser ablation were investigated. Porcine aorta samples were thermally altered in 160°C to 200°C glycerine baths and subsequently subjected to argon laser irradiation (488 - 514 nm). Experimental limitations, which resulted in slight compression and dehydration during heating, were accounted for with control samples. During laser irradiation, an infrared camera was used to infer thermal events associated with laser ablation of the heated, control, and untreated samples. Although changes in optical and thermal properties could not be isolated, temperature histories revealed statistically faster heating rates for samples in which more than about 6% water loss occurred during pre-treatment. Further, surface temperature recordings documented the explosive nature of cw laser ablation of soft biological media and demonstrated similar ablation threshold temperature ranges (170°C to 230°C) for most samples. The exceptions, tissue samples treated in a 200°C bath, did not display explosive ablation onset. Results suggest that temperature dependent mechanical properties of the tissue can be significantly degraded during heating and appear to dictate ablation initiation.

Original languageEnglish (US)
Title of host publicationAmerican Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD
Place of PublicationNew York, NY, United States
PublisherPubl by ASME
Pages79-83
Number of pages5
Volume189
ISBN (Print)0791808785
StatePublished - 1991
Externally publishedYes
EventWinter Annual Meeting of the American Society of Mechanical Engineers - Atlanta, GA, USA
Duration: Dec 1 1991Dec 6 1991

Other

OtherWinter Annual Meeting of the American Society of Mechanical Engineers
CityAtlanta, GA, USA
Period12/1/9112/6/91

Fingerprint

Continuous wave lasers
Laser ablation
Ablation
Tissue
Mechanical properties
Laser beam effects
Argon lasers
Heating
Temperature
Heating rate
Dehydration
Glycerol
Thermodynamic properties
Optical properties
Cameras
Infrared radiation
Water
Hot Temperature

ASJC Scopus subject areas

  • Fluid Flow and Transfer Processes
  • Mechanical Engineering

Cite this

LeCarpentier, G. L., Motamedi, M., & Welch, A. J. (1991). Thermally-induced changes in mechanical properties of tissue during CW laser ablation. In American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD (Vol. 189, pp. 79-83). New York, NY, United States: Publ by ASME.

Thermally-induced changes in mechanical properties of tissue during CW laser ablation. / LeCarpentier, Gerald L.; Motamedi, Massoud; Welch, A. J.

American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD. Vol. 189 New York, NY, United States : Publ by ASME, 1991. p. 79-83.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

LeCarpentier, GL, Motamedi, M & Welch, AJ 1991, Thermally-induced changes in mechanical properties of tissue during CW laser ablation. in American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD. vol. 189, Publ by ASME, New York, NY, United States, pp. 79-83, Winter Annual Meeting of the American Society of Mechanical Engineers, Atlanta, GA, USA, 12/1/91.
LeCarpentier GL, Motamedi M, Welch AJ. Thermally-induced changes in mechanical properties of tissue during CW laser ablation. In American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD. Vol. 189. New York, NY, United States: Publ by ASME. 1991. p. 79-83
LeCarpentier, Gerald L. ; Motamedi, Massoud ; Welch, A. J. / Thermally-induced changes in mechanical properties of tissue during CW laser ablation. American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD. Vol. 189 New York, NY, United States : Publ by ASME, 1991. pp. 79-83
@inproceedings{cb7837c55f194ff38a9221bc13285df3,
title = "Thermally-induced changes in mechanical properties of tissue during CW laser ablation",
abstract = "Thermal alterations of tissue as they relate to the initiation of continuous wave (cw) laser ablation were investigated. Porcine aorta samples were thermally altered in 160°C to 200°C glycerine baths and subsequently subjected to argon laser irradiation (488 - 514 nm). Experimental limitations, which resulted in slight compression and dehydration during heating, were accounted for with control samples. During laser irradiation, an infrared camera was used to infer thermal events associated with laser ablation of the heated, control, and untreated samples. Although changes in optical and thermal properties could not be isolated, temperature histories revealed statistically faster heating rates for samples in which more than about 6{\%} water loss occurred during pre-treatment. Further, surface temperature recordings documented the explosive nature of cw laser ablation of soft biological media and demonstrated similar ablation threshold temperature ranges (170°C to 230°C) for most samples. The exceptions, tissue samples treated in a 200°C bath, did not display explosive ablation onset. Results suggest that temperature dependent mechanical properties of the tissue can be significantly degraded during heating and appear to dictate ablation initiation.",
author = "LeCarpentier, {Gerald L.} and Massoud Motamedi and Welch, {A. J.}",
year = "1991",
language = "English (US)",
isbn = "0791808785",
volume = "189",
pages = "79--83",
booktitle = "American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD",
publisher = "Publ by ASME",

}

TY - GEN

T1 - Thermally-induced changes in mechanical properties of tissue during CW laser ablation

AU - LeCarpentier, Gerald L.

AU - Motamedi, Massoud

AU - Welch, A. J.

PY - 1991

Y1 - 1991

N2 - Thermal alterations of tissue as they relate to the initiation of continuous wave (cw) laser ablation were investigated. Porcine aorta samples were thermally altered in 160°C to 200°C glycerine baths and subsequently subjected to argon laser irradiation (488 - 514 nm). Experimental limitations, which resulted in slight compression and dehydration during heating, were accounted for with control samples. During laser irradiation, an infrared camera was used to infer thermal events associated with laser ablation of the heated, control, and untreated samples. Although changes in optical and thermal properties could not be isolated, temperature histories revealed statistically faster heating rates for samples in which more than about 6% water loss occurred during pre-treatment. Further, surface temperature recordings documented the explosive nature of cw laser ablation of soft biological media and demonstrated similar ablation threshold temperature ranges (170°C to 230°C) for most samples. The exceptions, tissue samples treated in a 200°C bath, did not display explosive ablation onset. Results suggest that temperature dependent mechanical properties of the tissue can be significantly degraded during heating and appear to dictate ablation initiation.

AB - Thermal alterations of tissue as they relate to the initiation of continuous wave (cw) laser ablation were investigated. Porcine aorta samples were thermally altered in 160°C to 200°C glycerine baths and subsequently subjected to argon laser irradiation (488 - 514 nm). Experimental limitations, which resulted in slight compression and dehydration during heating, were accounted for with control samples. During laser irradiation, an infrared camera was used to infer thermal events associated with laser ablation of the heated, control, and untreated samples. Although changes in optical and thermal properties could not be isolated, temperature histories revealed statistically faster heating rates for samples in which more than about 6% water loss occurred during pre-treatment. Further, surface temperature recordings documented the explosive nature of cw laser ablation of soft biological media and demonstrated similar ablation threshold temperature ranges (170°C to 230°C) for most samples. The exceptions, tissue samples treated in a 200°C bath, did not display explosive ablation onset. Results suggest that temperature dependent mechanical properties of the tissue can be significantly degraded during heating and appear to dictate ablation initiation.

UR - http://www.scopus.com/inward/record.url?scp=0026407943&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026407943&partnerID=8YFLogxK

M3 - Conference contribution

SN - 0791808785

VL - 189

SP - 79

EP - 83

BT - American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD

PB - Publ by ASME

CY - New York, NY, United States

ER -