TY - JOUR
T1 - Thoracic imaging of coronavirus disease 2019 (COVID-19) in children
T2 - a series of 91 cases
AU - Collaborators of the European Society of Paediatric Radiology Cardiothoracic Task Force
AU - Caro-Dominguez, Pablo
AU - Shelmerdine, Susan Cheng
AU - Toso, Seema
AU - Secinaro, Aurelio
AU - Toma, Paolo
AU - Damasio, Maria Beatrice
AU - Navallas, María
AU - Riaza-Martin, Lucia
AU - Gomez-Pastrana, David
AU - Ghadimi Mahani, Maryam
AU - Desoky, Sarah M.
AU - Ugas Charcape, Carlos F.
AU - Almanza-Aranda, Judith
AU - Ucar, Maria Elena
AU - Lovrenski, Jovan
AU - Gorkem, Sureyya Burcu
AU - Alexopoulou, Efthymia
AU - Ciet, Pierluigi
AU - van Schuppen, Joost
AU - Ducou le Pointe, Hubert
AU - Goo, Hyun Woo
AU - Kellenberger, Christian J.
AU - Raissaki, Maria
AU - Owens, Catherine M.
AU - Hirsch, Franz Wolfgang
AU - van Rijn, Rick R.
AU - Arthurs, Owen
AU - Bannier, Michiel
AU - Bianco, Francesco
AU - Borazjani, Roham
AU - Born, Mark
AU - Buschl, Jasmin
AU - Lacalamita, Marirosa Cristallo
AU - De Luca, Francesca
AU - Di Maurizio, Marco
AU - Finazzo, Francesca
AU - Jablonka, Karsten
AU - Jenkins, Mark
AU - Kamali, Karmella
AU - Macconi, Letizia
AU - Marín, Carlos
AU - León, María Martínez
AU - Morel, Baptiste
AU - Goitia, Inmaculada Mota
AU - Napolitano, Marcello
AU - Pan, Nin Yuan
AU - Pourbkhtyaran, Elham
AU - Prüfer, Friederike
AU - Rossi, Enrica
AU - Ruzal-Shapiro, Carrie
N1 - Publisher Copyright:
© 2020, Springer-Verlag GmbH Germany, part of Springer Nature.
PY - 2020/9/1
Y1 - 2020/9/1
N2 - Background: Pulmonary infection with SARS-CoV-2 virus (severe acute respiratory syndrome coronavirus 2; COVID-19) has rapidly spread worldwide to become a global pandemic. Objective: To collect paediatric COVID-19 cases worldwide and to summarize both clinical and imaging findings in children who tested positive on polymerase chain reaction testing for SARS-CoV-2. Materials and methods: Data were collected by completion of a standardised case report form submitted to the office of the European Society of Paediatric Radiology from March 12 to April 8, 2020. Chest imaging findings in children younger than 18 years old who tested positive on polymerase chain reaction testing for SARS-CoV-2 were included. Representative imaging studies were evaluated by multiple senior paediatric radiologists from this group with expertise in paediatric chest imaging. Results: Ninety-one children were included (49 males; median age: 6.1 years, interquartile range: 1.0 to 13.0 years, range: 9 days–17 years). Most had mild symptoms, mostly fever and cough, and one-third had coexisting medical conditions. Eleven percent of children presented with severe symptoms and required intensive unit care. Chest radiographs were available in 89% of patients and 10% of them were normal. Abnormal chest radiographs showed mainly perihilar bronchial wall thickening (58%) and/or airspace consolidation (35%). Computed tomography (CT) scans were available in 26% of cases, with the most common abnormality being ground glass opacities (88%) and/or airspace consolidation (58%). Tree in bud opacities were seen in 6 of 24 CTs (25%). Lung ultrasound and chest magnetic resonance imaging were rarely utilized. Conclusion: It seems unnecessary to perform chest imaging in children to diagnose COVID-19. Chest radiography can be used in symptomatic children to assess airway infection or pneumonia. CT should be reserved for when there is clinical concern to assess for possible complications, especially in children with coexisting medical conditions.
AB - Background: Pulmonary infection with SARS-CoV-2 virus (severe acute respiratory syndrome coronavirus 2; COVID-19) has rapidly spread worldwide to become a global pandemic. Objective: To collect paediatric COVID-19 cases worldwide and to summarize both clinical and imaging findings in children who tested positive on polymerase chain reaction testing for SARS-CoV-2. Materials and methods: Data were collected by completion of a standardised case report form submitted to the office of the European Society of Paediatric Radiology from March 12 to April 8, 2020. Chest imaging findings in children younger than 18 years old who tested positive on polymerase chain reaction testing for SARS-CoV-2 were included. Representative imaging studies were evaluated by multiple senior paediatric radiologists from this group with expertise in paediatric chest imaging. Results: Ninety-one children were included (49 males; median age: 6.1 years, interquartile range: 1.0 to 13.0 years, range: 9 days–17 years). Most had mild symptoms, mostly fever and cough, and one-third had coexisting medical conditions. Eleven percent of children presented with severe symptoms and required intensive unit care. Chest radiographs were available in 89% of patients and 10% of them were normal. Abnormal chest radiographs showed mainly perihilar bronchial wall thickening (58%) and/or airspace consolidation (35%). Computed tomography (CT) scans were available in 26% of cases, with the most common abnormality being ground glass opacities (88%) and/or airspace consolidation (58%). Tree in bud opacities were seen in 6 of 24 CTs (25%). Lung ultrasound and chest magnetic resonance imaging were rarely utilized. Conclusion: It seems unnecessary to perform chest imaging in children to diagnose COVID-19. Chest radiography can be used in symptomatic children to assess airway infection or pneumonia. CT should be reserved for when there is clinical concern to assess for possible complications, especially in children with coexisting medical conditions.
KW - COVID-19
KW - Children
KW - Computed tomography
KW - Coronavirus
KW - Imaging
KW - Lower respiratory tract infection
KW - Pneumonitis
KW - Radiography
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U2 - 10.1007/s00247-020-04747-5
DO - 10.1007/s00247-020-04747-5
M3 - Article
C2 - 32749530
AN - SCOPUS:85088995507
SN - 0301-0449
VL - 50
SP - 1354
EP - 1368
JO - Pediatric radiology
JF - Pediatric radiology
IS - 10
ER -