Thrombotic microangiopathy as a complication of medicinal leech therapy

Mohammadali Mohajel Shoja, Jalal Etemadi, Mohammad R. Ardalan, Roza Motavali, R. Shane Tubbs

Research output: Contribution to journalArticle

5 Scopus citations


Medicinal leeches (hirudo medicinalis) are increasingly used as a useful therapeutic option in various medical and surgical settings. The potential complications associated with this therapy include infections with Aeromonas species, bleeding, anemia, and allergic reactions. We describe a patient who developed thrombotic microangiopathy and acute renal failure following leech therapy. It is proposed that the series of nonhuman proteins within leech saliva may be capable of injuring the endothelium.

Original languageEnglish (US)
Pages (from-to)845-847
Number of pages3
JournalSouthern medical journal
Issue number8
StatePublished - Aug 1 2008
Externally publishedYes



  • Endothelium
  • Leech
  • Renal failure
  • Thrombotic microan-giopathy

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Mohajel Shoja, M., Etemadi, J., Ardalan, M. R., Motavali, R., & Tubbs, R. S. (2008). Thrombotic microangiopathy as a complication of medicinal leech therapy. Southern medical journal, 101(8), 845-847.