Thromboxane synthetase inhibition and thromboxane receptor blockade preserve pulmonary and circulatory function in a porcine burn sepsis model

Keyphrases

• Porcine 100%
• Pulmonary Function 100%
• Burn Sepsis 100%
• Sepsis Model 100%
• Synthetase 100%
• Receptor Blockade 100%
• Thromboxane 100%
• Thromboxane Receptor 100%
• Circulatory Function 100%
• Thromboxane A2 (TXA2) 80%
• Endotoxin 80%
• Cardiac Index 60%
• Thromboxane A2 Receptor 60%
• Sepsis 40%
• Severe Burns 40%
• Oxygen Delivery 40%
• Pulmonary Vascular Resistance 40%
• Adverse Effects 20%
• Receptor Antagonist 20%
• Pathophysiology 20%
• Thermal Injury 20%
• Placebo 20%
• Escherichia Coli 20%
• Oxygen Consumption 20%
• Receptor Blockers 20%
• Potential Gains 20%
• Saline Solution 20%
• Third-degree Burn 20%
• Severe Sepsis 20%
• Pulmonary Artery Catheter 20%
• Left Atrial 20%
• Shunt 20%
• Antagonist Treatment 20%
• Aorta Artery 20%
• Healthy pigs 20%

Medicine and Dentistry

• Sepsis 100%
• Thromboxane Synthase 100%
• Receptor Blocking 100%
• Thromboxane Receptor 100%
• Thermal Burn 75%
• Endotoxin 75%
• Resistance Index 50%
• Lung Vascular Resistance 50%
• Thromboxane A2 Receptor Blocking Agent 50%
• Adverse Event 25%
• Pathophysiology 25%
• Thermal Injury 25%
• Placebo 25%
• Mediator 25%
• Thromboxane A2 25%
• Side Effect 25%
• Synthetase 25%
• Oxygen Consumption 25%
• Escherichia Coli Endotoxin 25%
• Pulmonary Artery Catheter 25%
• Thromboxane A2 Receptor 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Sepsis 100%
• Pig 100%
• Thromboxane Synthase 100%
• Thromboxane Receptor 100%
• Burn 75%
• Endotoxin 75%
• Thromboxane A2 Receptor Blocking Agent 50%
• Adverse Event 25%
• Synthetase 25%
• Side Effect 25%
• Placebo 25%
• Thermal Injury 25%
• Pathophysiology 25%
• Thromboxane A2 25%
• Thromboxane A2 Receptor 25%
• Escherichia Coli Endotoxin 25%