Time-Dependent Variations in Urine Output After Renal Transplantation

H. T. Khosroshahi, R. Oskui, Mohammadali Mohajel Shoja, R. S. Tubbs, M. R. Ardalan

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Introduction: Diuresis begins soon after renal transplantation. Although controversial, early post kidney transplant urine volume may correlate with favorable short- and long-term allograft survival. The aim of the present study was to examine the potential changes in urine volume within the first 6 months after renal transplantation. Methods: In a prospective study, the first month serum creatinine level and daily urine volume were measured at 24 and 48 hours, and at 1 month after renal transplantation in patients with stable kidney function without the evidence of allograft rejection (n = 54). Fifteen patients were also followed for their urine output at least 6 months post kidney transplantation. Data are expressed in mean values ± SD. Statistical analysis was performed by SPSS version 13.0 using ANOVA. Correlation between continuous variables was performed using the Pearson test. The P value was set at .05. Results: The mean age of the renal allograft recipients was 35.5 ± 12.1 years with a male to female ratio of ∼1.3. The mean first month serum creatinine was 1.26 ± 0.4 mg/dL. The mean urine outputs were 10.06 ± 5.89, 5.45 ± 3.05, and 3.44 ± 1.25 L at 24 and 48 hours and 1 month post renal transplantation. Those patients who were followed for 6 months post transplant (n = 15) were observed to have a mean urine volume of 3.20 ± 1.24 L at the end of this period. This trend showed that urine volume steadily decreased from 24 and 48 hours to 1 month after renal transplantation (P < .05). However, urine volumes were rather comparable at one month and 6 months after transplantation (P > .05). A positive correlation was found between the first-month serum creatinine and the urine volume at one month (r = 0.302 and P = .035). Conclusion: Although urine volume showed considerable variation early after renal transplantation, it stabilized by 1 month after transplantation, which was also positively correlated with the first-month serum creatinine. Moreover, we concluded that in stable patients, the final urine output was related to early graft function.

Original languageEnglish (US)
Pages (from-to)932-933
Number of pages2
JournalTransplantation Proceedings
Volume39
Issue number4
DOIs
StatePublished - May 1 2007
Externally publishedYes

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Kidney Transplantation
Urine
Creatinine
Allografts
Serum
Transplants
Kidney
Diuresis
Analysis of Variance
Transplantation
Prospective Studies

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Khosroshahi, H. T., Oskui, R., Mohajel Shoja, M., Tubbs, R. S., & Ardalan, M. R. (2007). Time-Dependent Variations in Urine Output After Renal Transplantation. Transplantation Proceedings, 39(4), 932-933. https://doi.org/10.1016/j.transproceed.2007.04.006

Time-Dependent Variations in Urine Output After Renal Transplantation. / Khosroshahi, H. T.; Oskui, R.; Mohajel Shoja, Mohammadali; Tubbs, R. S.; Ardalan, M. R.

In: Transplantation Proceedings, Vol. 39, No. 4, 01.05.2007, p. 932-933.

Research output: Contribution to journalArticle

Khosroshahi, HT, Oskui, R, Mohajel Shoja, M, Tubbs, RS & Ardalan, MR 2007, 'Time-Dependent Variations in Urine Output After Renal Transplantation', Transplantation Proceedings, vol. 39, no. 4, pp. 932-933. https://doi.org/10.1016/j.transproceed.2007.04.006
Khosroshahi, H. T. ; Oskui, R. ; Mohajel Shoja, Mohammadali ; Tubbs, R. S. ; Ardalan, M. R. / Time-Dependent Variations in Urine Output After Renal Transplantation. In: Transplantation Proceedings. 2007 ; Vol. 39, No. 4. pp. 932-933.
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abstract = "Introduction: Diuresis begins soon after renal transplantation. Although controversial, early post kidney transplant urine volume may correlate with favorable short- and long-term allograft survival. The aim of the present study was to examine the potential changes in urine volume within the first 6 months after renal transplantation. Methods: In a prospective study, the first month serum creatinine level and daily urine volume were measured at 24 and 48 hours, and at 1 month after renal transplantation in patients with stable kidney function without the evidence of allograft rejection (n = 54). Fifteen patients were also followed for their urine output at least 6 months post kidney transplantation. Data are expressed in mean values ± SD. Statistical analysis was performed by SPSS version 13.0 using ANOVA. Correlation between continuous variables was performed using the Pearson test. The P value was set at .05. Results: The mean age of the renal allograft recipients was 35.5 ± 12.1 years with a male to female ratio of ∼1.3. The mean first month serum creatinine was 1.26 ± 0.4 mg/dL. The mean urine outputs were 10.06 ± 5.89, 5.45 ± 3.05, and 3.44 ± 1.25 L at 24 and 48 hours and 1 month post renal transplantation. Those patients who were followed for 6 months post transplant (n = 15) were observed to have a mean urine volume of 3.20 ± 1.24 L at the end of this period. This trend showed that urine volume steadily decreased from 24 and 48 hours to 1 month after renal transplantation (P < .05). However, urine volumes were rather comparable at one month and 6 months after transplantation (P > .05). A positive correlation was found between the first-month serum creatinine and the urine volume at one month (r = 0.302 and P = .035). Conclusion: Although urine volume showed considerable variation early after renal transplantation, it stabilized by 1 month after transplantation, which was also positively correlated with the first-month serum creatinine. Moreover, we concluded that in stable patients, the final urine output was related to early graft function.",
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