Tissue optical property measurements: Overestimation of absorption coefficient with spectrophotometric techniques

Jorge H. Torres, Ashley J. Welch, Inci Çilesiz, Massoud Motamedi

Research output: Contribution to journalArticle

30 Scopus citations


This study examines the validity of optical property measurements by comparing surface temperatures rises predicted by a well‐tested mathematical model with temperatures measured experimentally during laser irradiation. Analysis is based on the early temperature response that is proportional to the absorption coefficient. The results of the investigation suggest that values for tissue absorption coefficient can be greatly overestimated when current Spectrophotometric techniques are used. This seems especially true when a broad light beam and a low port‐to‐beam‐size ratio are used for transmission and reflection measurements with an integrating sphere. © 1994 Wiley‐Liss, Inc.

Original languageEnglish (US)
Pages (from-to)249-257
Number of pages9
JournalLasers in Surgery and Medicine
Issue number3
StatePublished - 1994



  • absorption coefficient
  • mathematical modeling
  • optical properties
  • spectrophotometer
  • temperature rise

ASJC Scopus subject areas

  • Surgery
  • Dermatology

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