Total energy expenditure in burned children using the doubly labeled water technique

M. I. Goran, E. J. Peters, D. N. Herndon, R. R. Wolfe

Research output: Contribution to journalArticlepeer-review

92 Scopus citations


Total energy expenditure (TEE) was measured in 15 burned children with the doubly labeled water technique. Application of the technique in burned children required evaluation of potential errors resulting from nutritional intake altering background enrichments during studies and from the high rate of water turnover relative to CO2 production. Five studies were discarded because of these potential problems. TEE was 1.33 ± 0.27 timers predicted basal energy expenditure (BEE), and in studies where resting energy expenditure (REE) was simultaneously measured, TEE was 1.18 ± 0.17 times REE, which in turn was 1.16 ± 0.10 times predicted BEE. TEE was significantly correlated with measured REE (r2 = 0.92) but not with predicted BEE. These studies substantiate the advantage of measuring REE to predict TEE in severely burned patients as opposed the relying on standardized equations. Therefore we recommend that optimal nutritional support will be achieved in convalescent burned children by multiplying REE by an activity factor of 1.2.

Original languageEnglish (US)
Pages (from-to)E576-E585
JournalAmerican Journal of Physiology - Endocrinology and Metabolism
Issue number4 22-4
StatePublished - 1990


  • body composition
  • burn injury
  • nutritional requirements

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Physiology
  • Physiology (medical)


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