Touch preparation of breast core needle specimens is a new method for same-day diagnosis

Rena Kass, Ronda S. Henry-Tillman, Jacob Nurko, Soheila Korourian, Anne T. Mancino, Maureen Colvert, Anita Johnson, Sarah Lane, Rakhshanda Layeeque, Harry Brown, Robert Fincher, Luis De Las Casas, James Waldron, Vicki Klimberg

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background: Touch preparation cytology (TPC) has proven to be a quick and accurate intraoperative diagnostic tool for excisional breast biopsy, margins and sentinel nodes. We hypothesized that TPC of core needle biopsy (CNB) specimens can provide a same-day diagnosis in the outpatient setting. Methods: Outpatients presenting with breast lesions underwent TPC of biopsy cores performed by biopsy gun or vacuum-assisted CNB. The TPC results were compared with the final diagnosis of CNB specimens. Results: In all, 199 CNB and TP were performed between August 1997 and October 2002. Twenty-nine percent of lesions were malignant. Touch preparation was deferred in 21% of cases. In the remaining 157 evaluable cases, TPC had an accuracy of 89% and a false negative rate of 26%. The sensitivity, specificity, positive predictive value and negative predictive value of TPC were 74%, 97%, 93%, and 86% respectively. Conclusions: Touch preparation cytology on CNB can be performed simply in the outpatient setting. Collaboration between the surgeon and pathologist allows TP to be an accurate means of same-day pathological determination.

Original languageEnglish (US)
Pages (from-to)737-742
Number of pages6
JournalAmerican Journal of Surgery
Volume186
Issue number6
DOIs
StatePublished - 2003
Externally publishedYes

Fingerprint

Touch
Needles
Large-Core Needle Biopsy
Breast
Cell Biology
Outpatients
Biopsy
Firearms
Vacuum
Sensitivity and Specificity

Keywords

  • Breast
  • Core biopsy
  • Diagnosis
  • Touch preparation

ASJC Scopus subject areas

  • Surgery

Cite this

Touch preparation of breast core needle specimens is a new method for same-day diagnosis. / Kass, Rena; Henry-Tillman, Ronda S.; Nurko, Jacob; Korourian, Soheila; Mancino, Anne T.; Colvert, Maureen; Johnson, Anita; Lane, Sarah; Layeeque, Rakhshanda; Brown, Harry; Fincher, Robert; De Las Casas, Luis; Waldron, James; Klimberg, Vicki.

In: American Journal of Surgery, Vol. 186, No. 6, 2003, p. 737-742.

Research output: Contribution to journalArticle

Kass, R, Henry-Tillman, RS, Nurko, J, Korourian, S, Mancino, AT, Colvert, M, Johnson, A, Lane, S, Layeeque, R, Brown, H, Fincher, R, De Las Casas, L, Waldron, J & Klimberg, V 2003, 'Touch preparation of breast core needle specimens is a new method for same-day diagnosis', American Journal of Surgery, vol. 186, no. 6, pp. 737-742. https://doi.org/10.1016/j.amjsurg.2003.08.026
Kass, Rena ; Henry-Tillman, Ronda S. ; Nurko, Jacob ; Korourian, Soheila ; Mancino, Anne T. ; Colvert, Maureen ; Johnson, Anita ; Lane, Sarah ; Layeeque, Rakhshanda ; Brown, Harry ; Fincher, Robert ; De Las Casas, Luis ; Waldron, James ; Klimberg, Vicki. / Touch preparation of breast core needle specimens is a new method for same-day diagnosis. In: American Journal of Surgery. 2003 ; Vol. 186, No. 6. pp. 737-742.
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