Abstract
The implications of the Keystone virus - Aedes atlanticus transmission cycle are explored in the context of a quantitative model. Among the variables considered are the vertical transmission rate, the effect of the virus upon vector fertility and survival, vector densities and distributions, the proportion susceptible in the vertebrate population, the attractiveness of different vertebrates to the vector and vector survival rates. The logical relationships between these several variables are explored. It is concluded that the current view of Keystone virus maintenance is quantitatively feasible, and that certain predictions may be made as to the magnitude of several parameters which have not yet been measured. Such predictions allow direct testing of the model. The general structure of the model is such that it may prove useful in describing the epidemiology of other vector-borne infections in which vertical transmission is essential for infection maintenance at certain periods of the year.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 322-338 |
| Number of pages | 17 |
| Journal | American Journal of Tropical Medicine and Hygiene |
| Volume | 27 |
| Issue number | 2 I |
| State | Published - 1978 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Parasitology
- Infectious Diseases
Cite this
Towards a quantitative understanding of the epidemiology of keystone virus in the Eastern United States. / Fine, P. E M; LeDuc, James.
In: American Journal of Tropical Medicine and Hygiene, Vol. 27, No. 2 I, 1978, p. 322-338.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Towards a quantitative understanding of the epidemiology of keystone virus in the Eastern United States
AU - Fine, P. E M
AU - LeDuc, James
PY - 1978
Y1 - 1978
N2 - The implications of the Keystone virus - Aedes atlanticus transmission cycle are explored in the context of a quantitative model. Among the variables considered are the vertical transmission rate, the effect of the virus upon vector fertility and survival, vector densities and distributions, the proportion susceptible in the vertebrate population, the attractiveness of different vertebrates to the vector and vector survival rates. The logical relationships between these several variables are explored. It is concluded that the current view of Keystone virus maintenance is quantitatively feasible, and that certain predictions may be made as to the magnitude of several parameters which have not yet been measured. Such predictions allow direct testing of the model. The general structure of the model is such that it may prove useful in describing the epidemiology of other vector-borne infections in which vertical transmission is essential for infection maintenance at certain periods of the year.
AB - The implications of the Keystone virus - Aedes atlanticus transmission cycle are explored in the context of a quantitative model. Among the variables considered are the vertical transmission rate, the effect of the virus upon vector fertility and survival, vector densities and distributions, the proportion susceptible in the vertebrate population, the attractiveness of different vertebrates to the vector and vector survival rates. The logical relationships between these several variables are explored. It is concluded that the current view of Keystone virus maintenance is quantitatively feasible, and that certain predictions may be made as to the magnitude of several parameters which have not yet been measured. Such predictions allow direct testing of the model. The general structure of the model is such that it may prove useful in describing the epidemiology of other vector-borne infections in which vertical transmission is essential for infection maintenance at certain periods of the year.
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UR - http://www.scopus.com/inward/citedby.url?scp=0017847896&partnerID=8YFLogxK
M3 - Article
C2 - 646025
AN - SCOPUS:0017847896
VL - 27
SP - 322
EP - 338
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
SN - 0002-9637
IS - 2 I
ER -