TY - JOUR
T1 - Transboundary spread of equine influenza viruses (H3N8) in West and Central Africa
T2 - Molecular characterization of identified viruses during outbreaks in Niger and Senegal, in 2019
AU - Diallo, Alpha Amadou
AU - Souley, Maman Moutari
AU - Issa Ibrahim, Abdoulkarim
AU - Alassane, Abdou
AU - Issa, Rahila
AU - Gagara, Haladou
AU - Yaou, Bachir
AU - Issiakou, Abdou
AU - Diop, Mariame
AU - Ba Diouf, Racky Oumar
AU - Lo, Fatou Tall
AU - Lo, Modou Moustapha
AU - Bakhoum, Thierno
AU - Sylla, Mamadou
AU - Seck, Momar Talla
AU - Meseko, Clement
AU - Shittu, Ismaila
AU - Cullinane, Ann
AU - Settypalli, Tirumala B.K.
AU - Lamien, Charles E.
AU - Dundon, William G.
AU - Cattoli, Giovanni
N1 - Publisher Copyright:
© 2020 Wiley-VCH GmbH
PY - 2021/5
Y1 - 2021/5
N2 - Since November 2018, several countries in West and Central Africa have reported mortalities in donkeys and horses. Specifically, more than 66,000 horses and donkeys have succumbed to disease in Burkina Faso, Chad, Cameroon, The Gambia, Ghana, Mali, Niger, Nigeria, and Senegal. Strangles caused by Streptococcus equi subsp equi, African Horse Sickness (AHS) virus, and Equine influenza virus (EIV) were all suspected as potential causative agents. This study reports the identification of EIV in field samples collected in Niger and Senegal. Phylogenetic analysis of the hemagglutinin and neuraminidase genes revealed that the identified viruses belonged to clade 1 of the Florida sublineage and were very similar to viruses identified in Nigeria in 2019. Interestingly, they were also more similar to EIVs from recent outbreaks in South America than to those in Europe and the USA. This is one of the first reports providing detailed description and characterization of EIVs in West and Central Africa region.
AB - Since November 2018, several countries in West and Central Africa have reported mortalities in donkeys and horses. Specifically, more than 66,000 horses and donkeys have succumbed to disease in Burkina Faso, Chad, Cameroon, The Gambia, Ghana, Mali, Niger, Nigeria, and Senegal. Strangles caused by Streptococcus equi subsp equi, African Horse Sickness (AHS) virus, and Equine influenza virus (EIV) were all suspected as potential causative agents. This study reports the identification of EIV in field samples collected in Niger and Senegal. Phylogenetic analysis of the hemagglutinin and neuraminidase genes revealed that the identified viruses belonged to clade 1 of the Florida sublineage and were very similar to viruses identified in Nigeria in 2019. Interestingly, they were also more similar to EIVs from recent outbreaks in South America than to those in Europe and the USA. This is one of the first reports providing detailed description and characterization of EIVs in West and Central Africa region.
KW - donkeys
KW - equine influenza virus
KW - H3N8
KW - Niger
KW - phylogenetic analysis
KW - Senegal
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U2 - 10.1111/tbed.13779
DO - 10.1111/tbed.13779
M3 - Article
C2 - 32770642
AN - SCOPUS:85089450865
SN - 1865-1674
VL - 68
SP - 1253
EP - 1262
JO - Transboundary and Emerging Diseases
JF - Transboundary and Emerging Diseases
IS - 3
ER -