Transboundary spread of equine influenza viruses (H3N8) in West and Central Africa: Molecular characterization of identified viruses during outbreaks in Niger and Senegal, in 2019

Alpha Amadou Diallo; Maman Moutari Souley; Abdoulkarim Issa Ibrahim; Abdou Alassane; Rahila Issa; Haladou Gagara; Bachir Yaou; Abdou Issiakou; Mariame Diop; Racky Oumar Ba Diouf; Fatou Tall Lo; Modou Moustapha Lo; Thierno Bakhoum; Mamadou Sylla; Momar Talla Seck; Clement Meseko; Ismaila Shittu; Ann Cullinane; Tirumala B.K. Settypalli; Charles E. Lamien; William G. Dundon; Giovanni Cattoli

doi:10.1111/tbed.13779

Transboundary spread of equine influenza viruses (H3N8) in West and Central Africa: Molecular characterization of identified viruses during outbreaks in Niger and Senegal, in 2019

Alpha Amadou Diallo
, Maman Moutari Souley
, Abdoulkarim Issa Ibrahim
, Abdou Alassane
, Rahila Issa
, Haladou Gagara
, Bachir Yaou
, Abdou Issiakou
, Mariame Diop
, Racky Oumar Ba Diouf
, Fatou Tall Lo
, Modou Moustapha Lo
, Thierno Bakhoum
, Mamadou Sylla
, Momar Talla Seck
, Clement Meseko
, Ismaila Shittu
, Ann Cullinane
, Tirumala B.K. Settypalli
, Charles E. Lamien

William G. Dundon, Giovanni Cattoli

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Since November 2018, several countries in West and Central Africa have reported mortalities in donkeys and horses. Specifically, more than 66,000 horses and donkeys have succumbed to disease in Burkina Faso, Chad, Cameroon, The Gambia, Ghana, Mali, Niger, Nigeria, and Senegal. Strangles caused by Streptococcus equi subsp equi, African Horse Sickness (AHS) virus, and Equine influenza virus (EIV) were all suspected as potential causative agents. This study reports the identification of EIV in field samples collected in Niger and Senegal. Phylogenetic analysis of the hemagglutinin and neuraminidase genes revealed that the identified viruses belonged to clade 1 of the Florida sublineage and were very similar to viruses identified in Nigeria in 2019. Interestingly, they were also more similar to EIVs from recent outbreaks in South America than to those in Europe and the USA. This is one of the first reports providing detailed description and characterization of EIVs in West and Central Africa region.

Original language	English (US)
Pages (from-to)	1253-1262
Number of pages	10
Journal	Transboundary and Emerging Diseases
Volume	68
Issue number	3
DOIs	https://doi.org/10.1111/tbed.13779
State	Published - May 2021
Externally published	Yes

Keywords

donkeys
equine influenza virus
H3N8
Niger
phylogenetic analysis
Senegal

ASJC Scopus subject areas

General Immunology and Microbiology
General Veterinary

Access to Document

10.1111/tbed.13779

Cite this

Diallo, A. A., Souley, M. M., Issa Ibrahim, A., Alassane, A., Issa, R., Gagara, H., Yaou, B., Issiakou, A., Diop, M., Ba Diouf, R. O., Lo, F. T., Lo, M. M., Bakhoum, T., Sylla, M., Seck, M. T., Meseko, C., Shittu, I., Cullinane, A., Settypalli, T. B. K., ... Cattoli, G. (2021). Transboundary spread of equine influenza viruses (H3N8) in West and Central Africa: Molecular characterization of identified viruses during outbreaks in Niger and Senegal, in 2019. Transboundary and Emerging Diseases, 68(3), 1253-1262. https://doi.org/10.1111/tbed.13779

Transboundary spread of equine influenza viruses (H3N8) in West and Central Africa: Molecular characterization of identified viruses during outbreaks in Niger and Senegal, in 2019. / Diallo, Alpha Amadou; Souley, Maman Moutari; Issa Ibrahim, Abdoulkarim et al.
In: Transboundary and Emerging Diseases, Vol. 68, No. 3, 05.2021, p. 1253-1262.

Research output: Contribution to journal › Article › peer-review

Diallo, AA, Souley, MM, Issa Ibrahim, A, Alassane, A, Issa, R, Gagara, H, Yaou, B, Issiakou, A, Diop, M, Ba Diouf, RO, Lo, FT, Lo, MM, Bakhoum, T, Sylla, M, Seck, MT, Meseko, C, Shittu, I, Cullinane, A, Settypalli, TBK, Lamien, CE, Dundon, WG & Cattoli, G 2021, 'Transboundary spread of equine influenza viruses (H3N8) in West and Central Africa: Molecular characterization of identified viruses during outbreaks in Niger and Senegal, in 2019', Transboundary and Emerging Diseases, vol. 68, no. 3, pp. 1253-1262. https://doi.org/10.1111/tbed.13779

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abstract = "Since November 2018, several countries in West and Central Africa have reported mortalities in donkeys and horses. Specifically, more than 66,000 horses and donkeys have succumbed to disease in Burkina Faso, Chad, Cameroon, The Gambia, Ghana, Mali, Niger, Nigeria, and Senegal. Strangles caused by Streptococcus equi subsp equi, African Horse Sickness (AHS) virus, and Equine influenza virus (EIV) were all suspected as potential causative agents. This study reports the identification of EIV in field samples collected in Niger and Senegal. Phylogenetic analysis of the hemagglutinin and neuraminidase genes revealed that the identified viruses belonged to clade 1 of the Florida sublineage and were very similar to viruses identified in Nigeria in 2019. Interestingly, they were also more similar to EIVs from recent outbreaks in South America than to those in Europe and the USA. This is one of the first reports providing detailed description and characterization of EIVs in West and Central Africa region.",

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AB - Since November 2018, several countries in West and Central Africa have reported mortalities in donkeys and horses. Specifically, more than 66,000 horses and donkeys have succumbed to disease in Burkina Faso, Chad, Cameroon, The Gambia, Ghana, Mali, Niger, Nigeria, and Senegal. Strangles caused by Streptococcus equi subsp equi, African Horse Sickness (AHS) virus, and Equine influenza virus (EIV) were all suspected as potential causative agents. This study reports the identification of EIV in field samples collected in Niger and Senegal. Phylogenetic analysis of the hemagglutinin and neuraminidase genes revealed that the identified viruses belonged to clade 1 of the Florida sublineage and were very similar to viruses identified in Nigeria in 2019. Interestingly, they were also more similar to EIVs from recent outbreaks in South America than to those in Europe and the USA. This is one of the first reports providing detailed description and characterization of EIVs in West and Central Africa region.

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Transboundary spread of equine influenza viruses (H3N8) in West and Central Africa: Molecular characterization of identified viruses during outbreaks in Niger and Senegal, in 2019

Abstract

Keywords

ASJC Scopus subject areas

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