Transdermal fentanyl improves management of postoperative hemorrhoidectomy pain

Michael Kilbride, Myron Morse, Anthony Senagore

    Research output: Contribution to journalArticlepeer-review

    49 Scopus citations


    PURPOSE: Outpatient postoperative hemorrhoidectomy pain remains a difficult problem. The purpose of this study is to evaluate the use of transdermal fentanyl for analgesia following hemorrhoidectomy. METHODS: Patients were prospectively randomized in a double-blind fashion to one of two groups, placebo or transdermal fentanyl. Forty-two patients were eligible for the study (placebo, 21; fentanyl, 17; 4 were excluded). A visual analog scale was used to evaluate postoperative pain (0 = no pain; 10 = worst pain). RESULTS: Fewer patients in the fentanyl group (10/17) required postoperative parental narcotics than the placebo group (21/21) (P<0.05 Fisher's exact test). The amount of narcotics consumed postoperatively was significantly less in the fentanyl group (97.05 mg of meperidine ± 23.27) than in the placebo group (236.19 ± 30.46) (P<.05 Student'st-tesf). Pain scores in the fentanyl group were significantly lower (less pain) than in the placebo group (P<0.05 Kruskal-Wallis). CONCLUSION: Results indicate that use of transdermal fentanyl provides an effective analgesic alternative that improves the transition to noninvasive outpatient pain management in the hemorrhoidectomy patient.

    Original languageEnglish (US)
    Pages (from-to)1070-1072
    Number of pages3
    JournalDiseases of the Colon & Rectum
    Issue number11
    StatePublished - Nov 1 1994


    • Hemorrhoidectomy
    • Pain
    • Postoperative
    • Transdermal fentanyl

    ASJC Scopus subject areas

    • Gastroenterology


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