Abstract
β-Polymerase is a vertebrate cellular DNA polymerase involved in gap-filling synthesis during some types of genomic DNA repair. We report that a cloned human β-polymerase promoter in a transient expression assay is activated by p21v-rasH expression in NIH 3T3 cells. A decanucleotide palindromic element, GTGACGTCAC, at positions -49 to -40 in the promoter is required for this ras-mediated stimulation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3852-3856 |
| Number of pages | 5 |
| Journal | Molecular and cellular biology |
| Volume | 10 |
| Issue number | 7 |
| State | Published - Jul 1990 |
| Externally published | Yes |
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology